Evidence map›Paper›PMID 28948172›Full record

ArticleJournal of diabetes research2017

Incidence and Mortality Rates and Clinical Characteristics of Type 1 Diabetes among Children and Young Adults in Cochabamba, Bolivia.

Elizabeth Duarte Gómez, Gabriel Andrew Gregory, Miriam Castrati Nostas, Angela Christine Middlehurst, Alicia Josephine Jenkins, Graham David Ogle

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Diabetes in Youth: A Global Perspective.Endocrinology and metabolism clinics of North America · 2021
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elizabeth Duarte GómezCentro Vivir con Diabetes, Av. Simón López, No. 375, Cochabamba, Bolivia.
Gabriel Andrew GregoryInternational Diabetes Federation Life for a Child Program, Glebe, NSW 2037, Australia.
Miriam Castrati NostasCentro Vivir con Diabetes, Av. Simón López, No. 375, Cochabamba, Bolivia.
Angela Christine MiddlehurstInternational Diabetes Federation Life for a Child Program, Glebe, NSW 2037, Australia.
Alicia Josephine JenkinsNHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW 2006, Australia.
Graham David OgleInternational Diabetes Federation Life for a Child Program, Glebe, NSW 2037, Australia.ORCID 0000-0002-2022-0866
The University of Sydney · AUDiabetes Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine incidence, mortality, and clinical status of youth with diabetes at the Centro Vivir con Diabetes, Cochabamba, Bolivia, with support from International Diabetes Federation Life for a Child Program.

methodsIncidence/mortality data analysis of all cases (<25 year (y)) diagnosed January 2005-February 2017 and cross-sectional data (December 2015).

resultsOver 12.2 years, 144 cases with type 1 diabetes (T1D) were diagnosed; 43.1% were male. Diagnosis age was 0.3-22.2 y; peak was 11-12 y. 11.1% were <5 y; 29.2%, 5-<10 y; 43.1%, 10-<15 y; 13.2%, 15-<20 y; and 3.5%, 20-<25 y. The youngest is being investigated for monogenic diabetes. Measured incidence in Cercado Province (Cochabamba Department) was 2.2/100,000 children < 15 y/y, with ≈80% ascertainment, giving total incidence of 2.7/100,000 children < 15 y/y. Two had died. Crude mortality rate was 2.3/1000 patient years. Clinical data on 141 cases <35 y: mean/median HbA1c was 8.5/8.2% (69/62 mmol/mol), levels higher in adolescents. Three were on renal replacement therapy; four others had substantial renal impairment. Elevated BMI, triglycerides, and cholesterol were common: 19.1%, 18.3%, and 39.1%, respectively.

conclusionsBolivia has low T1D incidence. Reasonable glycemic control is being achieved despite limited resources; however, some have serious complications and adverse cardiovascular risk factor profiles. Further attention is needed for complications.

Indexed as

Urban HealthAdolescentAdultBoliviaCardiovascular DiseasesChildChild, PreschoolCohort StudiesCost of IllnessCross-Sectional StudiesDiabetes Mellitus, Type 1Diabetic AngiopathiesDiabetic CardiomyopathiesFemaleFollow-Up StudiesHumans

Identifiers

PMID28948172
PMCPMC5602613
OpenAlexW2750904004

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.