Evidence map›Paper›PMID 28948164›Full record

Trial reportBioMed research international2017

Liver Adiposity and Metabolic Profile in Individuals with Chronic Spinal Cord Injury.

Kathleen C Rankin, Laura C O'Brien, Liron Segal, M Rehan Khan, Ashraf S Gorgey

Registry-linked trialOpen access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01652040 (Effects of Evoked Resistance Training and Testosterone After Spinal Cord Injury), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01652040 phase2 / phase3completednot on this map

Effects of Evoked Resistance Training and Testosterone After Spinal Cord Injury

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2012 to 2017Enrolled26ConditionsSpinal Cord InjuryArmsResistance Training and Testosterone Patches, Testosterone Patches
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kathleen C RankinSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, VA, USA.
Laura C O'BrienSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, VA, USA.
Liron SegalSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, VA, USA.
M Rehan KhanDepartment of Radiology, Virginia Commonwealth University, Richmond, VA, USA.
Ashraf S GorgeySpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, VA, USA.ORCID 0000-0002-9157-6034
Virginia Commonwealth University · USHunter Holmes McGuire VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo quantify liver adiposity using magnetic resonance imaging (MRI) and to determine its association with metabolic profile in men with spinal cord injury (SCI). MATERIALS AND

methodsMRI analysis of liver adiposity by fat signal fraction (FSF) and visceral adipose tissue (VAT) was completed on twenty participants. Intravenous glucose tolerance test was conducted to measure glucose effectiveness (

resultsAverage hepatic FSF was 3.7% ± 2.1. FSF was positively related to TG, non-HDL-C, fasting glucose, HbA1c, VAT, and tumor necrosis factor alpha (TNF-

conclusionsMRI noninvasively estimated hepatic adiposity in men with chronic SCI. FSF was associated with dysfunction in metabolic profile, central adiposity, and inflammation. Importantly, liver adiposity influenced metabolic profile independently of VAT. These findings highlight the significance of quantifying liver adiposity after SCI to attenuate the development of metabolic disorders.

Indexed as

AdiposityMagnetic Resonance ImagingAdolescentAdultChronic DiseaseHumansLiverMaleMiddle AgedSpinal Cord Injuries

Identifiers

PMID28948164
PMCPMC5602482
OpenAlexW2753860836

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.