ArticleRehabilitation oncology (American Physical Therapy Association. Oncology Section)2017
Feasibility and functional outcomes of children and adolescents undergoing preoperative chemotherapy prior to a limb-sparing procedure or amputation.
Article in Rehabilitation oncology (American Physical Therapy Association. Oncology Section), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04862130 (Rehabilitative Evaluation of Functional Abilities in Children/Adolescents Affected by Cancer), which is not on this map. Cited by 18 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Rehabilitative Evaluation of Functional Abilities in Children/Adolescents Affected by Cancer: a Validation Study of the GMFM-88 Scale and of the Functional Abilities Assessment in Pediatric Oncology (FAAP-O) Scale
Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Nutrition and physical activity interventions delivered to children and young people during cancer treatment: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Physical capacity in children and adolescents with newly diagnosed cancer: A systematic review and meta-analysis.Pediatric blood & cancer · 2024Pooled it
- Physical and functional performance assessment in pediatric oncology: a systematic review.Pediatric research · 2022Pooled it
- Physical therapy interventions, other than general physical exercise interventions, in children and adolescents before, during and following treatment for cancer.The Cochrane database of systematic reviews · 2021Pooled it
- Effects of Exercise Intervention on Quality of Life in Adolescent and Young Adult Cancer Patients and Survivors: A Meta-Analysis.Integrative cancer therapiesPooled it
- Longitudinal Functional Outcomes Among Survivors of Childhood Lower Extremity Osteosarcoma.Cancers · 2026Article
- Clinical outcomes measurement in pediatric lower limb prosthetics: A scoping review.Journal of pediatric rehabilitation medicine · 2024Article
- An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation.JMIR pediatrics and parenting · 2023Article
- Skeletal Muscle Measurements in Pediatric Hematology and Oncology: Essential Components to a Comprehensive Assessment.Children (Basel, Switzerland) · 2023Review
- Article
- Identification of Requirements for a Postoperative Pediatric Pain Risk Communication Tool: Focus Group Study With Clinicians and Family Members.JMIR pediatrics and parenting · 2022Article
- Promoting positive physical activity behaviors for children and adolescents undergoing acute cancer treatment: Development of the CanMOVE intervention using the Behavior Change Wheel.Frontiers in pediatrics · 2022Article
- Therapeutic exercise interventions in pediatric survivors of brain cancer and other solid tumors: A scoping review.Frontiers in pediatrics · 2022Article
- Skeletal Muscle and Childhood Cancer: Where are we now and where we go from here.Aging and cancer · 2021Article
- Cumulative Burden of Chronic Health Conditions in Adult Survivors of Osteosarcoma and Ewing Sarcoma: A Report from the St. Jude Lifetime Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- Alterations in Muscle Architecture: A Review of the Relevance to Individuals After Limb Salvage Surgery for Bone Sarcoma.Frontiers in pediatrics · 2020Article
- Physical Rehabilitation Practices for Children and Adolescents with Cancer in Canada.Physiotherapy Canada. Physiotherapie Canada · 2020Article
- A Scoping Review of Physical Therapy Interventions for Childhood Cancers.Physiotherapy Canada. Physiotherapie Canada · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSurvivors of lower extremity (LE) malignancies experience functional deficits. PURPOSE: The purpose of this prospective clinical trial was to determine feasibility and functional outcomes of adding pre-habilitation during the 10-12 week period prior to a planned surgery to remove the tumor in children and adolescents with a LE sarcoma.
designPilot study.
settingSt. Jude Children's Research Hospital (SJCRH). PATIENTS: Participants included 14 individuals between the ages of 8 and 20 years who were diagnosed with a LE sarcoma. Participant outcomes were compared to a control group of 35 individuals treated for osteosarcoma that obtained the same functional assessments but no pre-habilitation.
interventionThe intervention group received strengthening exercises and mobility training 3 times per week for 30-60 minutes for 10-12 weeks preoperatively. MEASUREMENTS: Participants completed the Functional Mobility Assessment (FMA) and measures of strength and range of motion (ROM) of bilateral lower extremities (BLEs) at baseline, after 10-12 weeks of preoperative PT, and at 20-22 weeks.
resultsTwelve participants completed at least 50% of their schedule pre-habilitative sessions. The intervention group scored significantly better on the FMA than the control group at weeks 20-22 (35.6 vs. 25.7, p .0267). No significant difference was found in ROM or strength. LIMITATIONS: Due to this study being a pilot study, the sample size was small. Therefore, we cannot infer generalizability.
conclusionsFindings suggest that those diagnosed with a LE malignancy awaiting a limb sparing procedure or amputation participate in at least 50% of scheduled PT sessions and benefit from them.
Indexed as
Identifiers
28948112PMC5609724W2811397544What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.