ArticleBrain and behavior2017
Open access · goldAbstract read
In one paragraph
Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Apolipoprotein E4 Polymorphism and Outcomes from Traumatic Brain Injury: A Living Systematic Review and Meta-Analysis.Journal of neurotrauma · 2021Pooled it
- Genetic Variants and Persistent Impairment Following Mild Traumatic Brain Injury: A Systematic Review.The Journal of head trauma rehabilitationPooled it
- Genetic factors complicating recovery in patients with brain injury: Possible link between injury severity and posttraumatic neurodegeneration related to intracerebral amyloid deposition - A narrative review.Surgical neurology international · 2026Review
- Association of Alzheimer's Disease Polygenic Risk Score with Concussion Severity and Recovery Metrics.Sports medicine (Auckland, N.Z.) · 2025Article
- Apolipoprotein-E4: risk of severe malaria and mortality and cognitive impairment in pediatric cerebral malaria.Pediatric research · 2024Article
- Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis.Environmental health : a global access science source · 2023Article
- A Framework to Advance Biomarker Development in the Diagnosis, Outcome Prediction, and Treatment of Traumatic Brain Injury.Journal of neurotrauma · 2022Review
- APOE-ε4 Is Associated With Reduced Verbal Memory Performance and Higher Emotional, Cognitive, and Everyday Executive Function Symptoms Two Months After Mild Traumatic Brain Injury.Frontiers in neurology · 2022Article
- Effects of sex and genotype in human APOE-targeted replacement mice on alcohol self-administration measured with the automated IntelliCage system before and after repeated mild traumatic brain injury.Alcoholism, clinical and experimental research · 2021Article
- Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.JAMA network open · 2021Article
- Genetic Variation and Impact on Outcome in Traumatic Brain Injury: an Overview of Recent Discoveries.Current neurology and neuroscience reports · 2021Review
- The Influence of Family History of Neurodegenerative Disease on Adolescent Concussion Outcomes.Journal of clinical medicine · 2021Article
- Apolipoprotein ɛ4 Status and Brain Structure 12 Months after Mild Traumatic Injury: Brain Age Prediction Using Brain Morphometry and Diffusion Tensor Imaging.Journal of clinical medicine · 2021Article
- APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid.Journal of Alzheimer's disease : JAD · 2021Article
- Integrative Neuroinformatics for Precision Prognostication and Personalized Therapeutics in Moderate and Severe Traumatic Brain Injury.Frontiers in neurology · 2021Review
- Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision.Journal of neurotrauma · 2020Review
- Exploring Neuronal Vulnerability to Head Trauma Using a Whole Exome Approach.Journal of neurotrauma · 2020Article
- Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence.International journal of molecular sciences · 2020Review
- Piperine Attenuates TBI-Induced Seizures via Inhibiting Cytokine-Activated Reactive Astrogliosis.Frontiers in neurology · 2020Article
- Intelligence across the seventh decade in patients with brain injuries acquired in young adulthood.Trends in neuroscience and education · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 10 institutions in 2 countries.
John K YueDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.ORCID 0000-0001-9694-7722
Caitlin K RobinsonDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
John F BurkeDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Ethan A WinklerDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Hansen DengDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Maryse C CnossenDepartment of Public Health Erasmus Medical Center Rotterdam The Netherlands.
Hester F LingsmaDepartment of Public Health Erasmus Medical Center Rotterdam The Netherlands.
Adam R FergusonDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Thomas W McAllisterDepartment of Psychiatry Indiana University School of Medicine Indianapolis IN USA.
Jonathan RosandProgram in Medical and Population Genetics The Broad Institute at MIT and Harvard Cambridge MA USA.
Esteban G BurchardDepartment of Bioengineering and Therapeutic Sciences University of California, San Francisco San Francisco CA USA.
Marco D SoraniDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Sourabh SharmaDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Jessica L NielsonDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Gabriela G SatrisDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Jason F TalbottBrain and Spinal Injury Center San Francisco General Hospital San Francisco CA USA.
Phiroz E TaraporeDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Frederick K KorleyDepartment of Emergency Medicine University of Michigan at Ann Arbor Ann Arbor MI USA.
Kevin K W WangDepartments of Psychiatry and Neuroscience University of Florida Gainesville FL USA.
Esther L YuhDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Pratik MukherjeeDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
Ramon Diaz-ArrastiaDepartment of Neurology University of Pennsylvania Philadelphia PA USA.
Alex B ValadkaDepartment of Neurological Surgery Virginia Commonwealth University Richmond VA USA.
David O OkonkwoDepartment of Neurological Surgery University of Pittsburgh Medical Center Pittsburgh PA USA.
Geoffrey T ManleyDepartment of Neurological Surgery University of California, San Francisco San Francisco CA USA.
TRACK‐TBI Investigators
San Francisco General Hospital · USUniversity of California, San Francisco · USErasmus MC · NLBroad Institute · USIndiana University School of MedicineUniversity of Florida · USUniversity of Michigan · USUniversity of Pennsylvania · USUniversity of Pittsburgh Medical Center · USVirginia Commonwealth University · US
Funding
Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1MTransforming Traumatic Brain Injury Research and Clinical CareRC2NS069409 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MANLEY, GEOFFREY T · 2009 to 2011
$4.3MNINDS NIH HHS RC2 NS069409NINDS NIH HHS U01 NS086090
Abstract
introductionThe apolipoprotein E (
methodsmTBI patients (Glasgow Coma Scale score 13-15, no neurosurgical intervention, extracranial Abbreviated Injury Scale score ≤1) aged ≥18 years with
resultsIn 114 mTBI patients (
conclusionThe
Indexed as
AllelesAdultApolipoprotein E4Apolipoproteins EBrain ConcussionFemaleGenotypeHumansMaleMemoryMemory DisordersMiddle AgedApolipoprotein E4Apolipoproteins Eapolipoprotein Egenetic factorshuman studiesoutcome measurestraumatic brain injuryverbal memory
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.