Evidence map›Paper›PMID 28948065›Full record

ArticleBrain and behavior2017

Genetic alterations of IDH1 and Vegf in brain tumors.

Silvia Veganzones, Virginia de la Orden, Lucía Requejo, Beatriz Mediero, María Luisa González, Náyade Del Prado, Carmen Rodríguez García, Raquel Gutiérrez-González, Alvaro Pérez-Zamarrón, Armando Martínez and 5 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Silvia VeganzonesDepartment of Clinical Analysis Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Virginia de la OrdenDepartment of Clinical Analysis Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Lucía RequejoDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Beatriz MedieroDepartment of Clinical Analysis Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
María Luisa GonzálezDepartment of Clinical Analysis Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Náyade Del PradoDepartment of Epidemiology Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Carmen Rodríguez GarcíaDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Raquel Gutiérrez-GonzálezDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Alvaro Pérez-ZamarrónDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Armando MartínezDepartment of Pathology Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Marisa L MaestroDepartment of Clinical Analysis Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Horacio Mario ZimmanDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Anna González-NeiraDepartment of Clinical Analysis Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Jesús VaqueroDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.
Gregorio Rodríguez-BotoDepartment of Neurosurgery Hospital Clínico San Carlos and Hospital Universitario Puerta de Hierro-Majadahonda Majadahonda Madrid Spain.ORCID 0000-0003-4212-9374
Hospital Clínico San Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluates the presence of R132H mutation in isocitrate dehydrogenase (

methodsA cohort of 80 patients surgically treated at Hospital Clínico San Carlos, Madrid, between March 2004 and November 2012, was analyzed. Tumors were distributed in 73 primary brain tumors (gliomas, meningiomas, hemangiopericytomas and hemangioblastomas) and seven secondary tumors evolved from a low grade glioma, thus providing a mixed sample.

results

conclusions

Indexed as

Brain NeoplasmsGliomaHemangioblastomaHemangiopericytomaMeningiomaCohort StudiesDisease-Free SurvivalFemaleHumansIsocitrate DehydrogenaseMaleMiddle AgedMutationPolymorphism, GeneticPrognosisSpainIDH1 protein, humanIsocitrate DehydrogenaseVascular Endothelial Growth Factor AVEGFA protein, humanbrain tumorsgliomaIDH1survivalVEGF

Identifiers

PMID28948065
PMCPMC5607534
OpenAlexW2741627931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.