Evidence map›Paper›PMID 28947959›Full record

ArticleOncotarget2017

ColXV promotes adipocyte differentiation via inhibiting DNA methylation and cAMP/PKA pathway in mice.

Guannv Liu, Meihang Li, Yatao Xu, Song Wu, Muhammad Saeed, Chao Sun

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. The Characterization and Differential Analysis of mAnimals : an open access journal from MDPI · 2023
    Article
  6. Article
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  9. Article
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  11. Article
  12. Calcium Signaling Pathways: Key Pathways in the Regulation of Obesity.International journal of molecular sciences · 2019
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guannv Liu *College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100, China.
Meihang Li *College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100, China.
Yatao XuCollege of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100, China.
Song WuCollege of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100, China.
Muhammad SaeedCollege of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100, China.
Chao SunCollege of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi, 712100, China.
Northwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular matrix (ECM), as an essential component of adipose tissue, not only provides mechanical support for adipocyte growth, but also participates in ECM-adipocyte communication via various secreted proteins, including highly enriched collagens. Collagen XV (ColXV) is a secreted non-fibrillar collagen within ECM Basement Membrane (BM) zones and well recognized as a tumor suppressor. However, the role of ColXV in adipose tissue is still unknown. In this study, high fat diet (HFD) fed mice were used as obese model, in which we deeply investigated the interaction between ColXV and adipocyte differentiation or adipose metabolism. We found great elevated ColXV expression and positive effect of ColXV on lipid deposition during adipocyte differentiation or obesity both

Indexed as

adipocyte differentiationcAMP/PKA pathwayColXVCREBmethylation

Identifiers

PMID28947959
PMCPMC5601127
OpenAlexW2626035894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.