Evidence map›Paper›PMID 28947884›Full record

ArticleContemporary oncology (Poznan, Poland)2017

Expression of vitamin D receptor and vitamin D status in patients with oral neoplasms and effect of vitamin D supplementation on quality of life in advanced cancer treatment.

Akshay Anand, Suyash Singh, Abhinav A Sonkar, Nuzhat Husain, Kul Ranjan Singh, Sudhir Singh, Jitendra K Kushwaha

4 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Contemporary oncology (Poznan, Poland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04096846 unknown statusnot on this mapstarted 2019, after this paper: background citation

Relationship Between Vitamin D Deficiency and Oral Mucositis in Patients With Acute Lymphoblastic Leukemia Receiving Methotrexate in South Egypt Cancer Institute , a Prospective Study

TypeobservationalSponsorAssiut UniversityRan2019 to 2020Enrolled100ConditionsAcute Lymphoblastic LeukemiaArmslaboratory investigation
NCT04308161 phase2unknown statusnot on this mapstarted 2019, after this paper: background citation

The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis

TypeinterventionalSponsorHams Hamed AbdelrahmanRan2019 to 2020Enrolled45ConditionsOral Mucositis Due to RadiationArmsvitamin D oral gel, Miconazole Topical Gel, BBC oral spray, Oracure gel, Alkamisr sachets
NCT04488237 unknown statusnot on this mapstarted 2020, after this paper: background citation

Effect of Vitamin D Administration on Methotrexate Adverse Effects in Patients With Acute Lymphoblastic Leukemia

TypeobservationalSponsorAssiut UniversityRan2020 to 2021Enrolled50ConditionsAcute Lymphoblastic LeukemiaArmsVitamin D
NCT06100692 unknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Prophylactic Use of Oral Vitamin D and Zinc in Management of the Severity of Radiation Induced Oral Mucositis of Head and Neck Cancer Patients

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled100ConditionsOncologyArmsVitamin D
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Akshay AnandKing George's Medical University, India.
Suyash SinghKing George's Medical University, India.
Abhinav A SonkarKing George's Medical University, India.
Nuzhat HusainRML Institute Of Medical Sciences UP, India.
Kul Ranjan SinghKing George's Medical University, India.
Sudhir SinghKing George's Medical University, India.
Jitendra K KushwahaKing George's Medical University, India.
King George's Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim of the studyVitamin D receptor (VDR) expression and serum vitamin D scores in oral premalignant lesions and oral cancer have not been widely analyzed. The role of vitamin D supplementation in advanced oral cancer for improving quality of life (QOL) is also a matter of research. MATERIAL AND

methodsVitamin D receptor expression and vitamin D scores were analyzed in normal oral mucosa (

resultsVitamin D receptor expression was increased in oral neoplastic lesions. Vitamin D scores were significantly lower in cases compared to healthy controls (

conclusionsVitamin D receptor expression is increased in premalignant lesions and oral cancer. Vitamin D insufficiency and deficiency are prevalent in patients with oral neoplastic lesions. Vitamin D supplementation has a role in reducing treatment-related toxicities, especially in advanced cancer.

Indexed as

calcidiol levelscalcitriol receptororal neoplasmsquality of life

Identifiers

PMID28947884
PMCPMC5611504
OpenAlexW2729091996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.