Evidence map›Paper›PMID 28947858›Full record

ReviewMediators of inflammation2017

Psoriasis and Cardiovascular Risk-Do Promising New Biomarkers Have Clinical Impact?

Sirje Kaur, Külli Kingo, Mihkel Zilmer

Open access · goldAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Psoriasis and Cardiovascular Disease: Lesion Beyond the Skin.Arquivos brasileiros de cardiologia · 2019
    Article
  7. Article
  8. Psoriasis & cardiovascular morbidity: The missing links?The Indian journal of medical research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sirje KaurClinic of Dermatology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0001-9346-7985
Külli KingoClinic of Dermatology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Mihkel ZilmerInstitute of Biomedicine and Translational Medicine, Department of Biochemistry, The Centre of Excellence for Genomics and Translational Medicine, University of Tartu, 19 Ravila St., 50411 Tartu, Estonia.
Tartu University Hospital · EEUniversity of Tartu · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies suggest an increased prevalence of cardiovascular disease (CVD) in patients with psoriasis (PS). Therefore, emphasis has lately been laid on the necessity for clinical evaluation of the risk of CVD in these patients. The systemic inflammatory markers C-reactive protein (CRP) and interleukin- (IL-) 6, which have long been used to predict future CVD in the general population, are increased manyfold in patients with PS. Lipid abnormalities characterized by elevated triglycerides, low HDL cholesterol, and higher concentrations of LDL cholesterol and its oxidized form are also prevalent in patients. There is a need for additional laboratory markers for the assessment of cardiovascular status of patients with PS. Due to frequent comorbid overweight and obesity, biologically active compounds produced by adipocytes may have an impact on monitoring the status of the cardiovascular system of patients with PS. For this purpose, two adipokines, adiponectin and leptin, have been most extensively studied. The review focuses on some inflammatory and oxidative stress aspects in patients with PS through the analysis of the impact of prominent adipokines and oxidized low-density lipoprotein (oxLDL) to assess their eligibility for clinical practice as markers of CVD risk in patients with PS.

Indexed as

AdipokinesAnimalsBiomarkersCardiovascular DiseasesCholesterolCholesterol, HDLCholesterol, LDLC-Reactive ProteinHumansInterleukin-6LeptinLipoproteins, LDLPsoriasisRisk FactorsAdipokinesBiomarkersCholesterolCholesterol, HDLCholesterol, LDLC-Reactive ProteinInterleukin-6LeptinLipoproteins, LDLoxidized low density lipoprotein

Identifiers

PMID28947858
PMCPMC5602647
OpenAlexW2751318071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.