Evidence map›Paper›PMID 28947768›Full record

ArticleScientific reports2017

Ventricular myocardium development and the role of connexins in the human fetal heart.

Eleftheria Pervolaraki, James Dachtler, Richard A Anderson, Arun V Holden

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Recent Advances in Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Promoted by Mechanical Stretch.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Review
  8. Article
  9. Insoluble Aβ overexpression in anDisease models & mechanisms · 2019
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Eleftheria PervolarakiSchool of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, UK. fbsepe@leeds.ac.uk.ORCID 0000-0002-2842-7562
James DachtlerDepartment of Psychology, Durham University, Durham, DH1 3LE, UK.
Richard A AndersonMRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, EH16 4TJ, UK.ORCID 0000-0002-7495-518X
Arun V HoldenSchool of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, UK.ORCID 0000-0003-3731-2561
University of Leeds · GBDurham University · GBMRC Centre for Reproductive Health · GB

Funding

Medical Research Council G1002118Medical Research Council G1100357Wellcome Trust
6 · The paper itself

Abstract

The developmental timeline of the human heart remains elusive. The heart takes on its characteristic four chambered appearance by ~56 days gestational age (DGA). However, owing to the complexities (both technical and logistical) of exploring development in utero, we understand little of how the ventricular walls develop. To address this, we employed diffusion tensor magnetic resonance imaging to explore the architecture and tissue organization of the developing heart aged 95-143 DGA. We show that fractional anisotropy increases (from ~0.1 to ~0.5), diffusion coefficients decrease (from ~1 × 10

Indexed as

Connexin 43ConnexinsDiffusion Tensor ImagingFetal HeartGap Junction alpha-5 ProteinHeart VentriclesHumansMyocardiumConnexin 43ConnexinsGap Junction alpha-5 ProteinGJA1 protein, human

Identifiers

PMID28947768
PMCPMC5612926
OpenAlexW2755042067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.