Evidence map›Paper›PMID 28947597›Full record

ArticlePhysiological reports2017

C-reactive protein improves the ability to detect cardiometabolic risk in mild-to-moderate obstructive sleep apnea.

Jordan Gaines, Lan Kong, Menghan Li, Julio Fernandez-Mendoza, Edward O Bixler, Maria Basta, Alexandros N Vgontzas

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Effect of age on the association of obstructive sleep apnea with metabolic syndrome among obese and nonobese adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  2. Article
  3. Circulating C-reactive protein levels in patients with suspected obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  4. Article
  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jordan GainesDepartment of Psychiatry, Sleep Research and Treatment Center Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Lan KongDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Menghan LiDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Julio Fernandez-MendozaDepartment of Psychiatry, Sleep Research and Treatment Center Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Edward O BixlerDepartment of Psychiatry, Sleep Research and Treatment Center Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Maria BastaDepartment of Psychiatry, Sleep Research and Treatment Center Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Alexandros N VgontzasDepartment of Psychiatry, Sleep Research and Treatment Center Pennsylvania State University College of Medicine, Hershey, Pennsylvania avgontzas@psu.edu.
Pennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA), particularly in the mild-to-moderate range, affects up to 40% of the adult general population. While it is clear that treatment should be pursued in severe cases of OSA, when and how to best treat OSA in the mild-to-moderate range remains complicated, despite its high prevalence. The aim of this study was to compare the relative utility of apnea/hypopnea index (AHI) versus a biomarker of inflammation, C-reactive protein (CRP), in identifying the presence and severity of hypertension and hyperglycemia. Middle-aged (

Indexed as

BiomarkersBlood PressureBody Mass IndexC-Reactive ProteinFemaleHumansHyperglycemiaHypertensionMaleMiddle AgedSleep Apnea, ObstructiveBiomarkersC-Reactive ProteinBiomarkerhyperglycemiahypertensioninflammationmetabolic syndromeobstructive sleep apnea

Identifiers

PMID28947597
PMCPMC5617934
OpenAlexW2760348930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.