ArticlePhysiological reports2017
miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice.
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Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
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Who cites it
20 citing papers in PubMed, 24 citations in OpenAlex.
- Congenital vs adult-onset estrogen deficiency in female mice: physiological effects and implications for therapy.The Journal of endocrinology · 2026Article
- Comparative Analysis of Gene and MicroRNA Expression in Subcutaneous Adipose Tissue in Metabolically Healthy and Unhealthy Obesity.International journal of molecular sciences · 2025Article
- MicroRNAs in adipose tissue fibrosis: Mechanisms and therapeutic potential.Genes & diseases · 2025Review
- Preliminary study on the active substances and cellular pathways of lactic acid bacteria for colorectal cancer treatment.Journal of Cancer · 2024Article
- Skeletal Muscle Endogenous Estrogen Production Ameliorates the Metabolic Consequences of a High-Fat Diet in Male Mice.Endocrinology · 2023Article
- Changes in subcutaneous adipose tissue microRNA expression in response to exercise training in obese African women.Scientific reports · 2022Article
- Role of microRNA in Endocrine Disruptor-Induced Immunomodulation of Metabolic Health.Metabolites · 2022Review
- Augmenting Skeletal Muscle Estrogen Does not Prevent or Rescue Obesity-linked Metabolic Impairments in Female Mice.Endocrinology · 2022Article
- Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice.Scientific reports · 2022Article
- Review
- Macrophage tumor necrosis factor-alpha deletion does not protect against obesity-associated metabolic dysfunction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Advances in scarless foetal wound healing and prospects for scar reduction in adults.Cell proliferation · 2020Review
- Impact of weight loss and partial weight regain on immune cell and inflammatory markers in adipose tissue in male mice.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Adipose Tissue Fibrosis: Mechanisms, Models, and Importance.International journal of molecular sciences · 2020Review
- Extrinsic and Intrinsic Immunometabolism Converge: Perspectives on Future Research and Therapeutic Development for Obesity.Current obesity reports · 2019Review
- Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice.World journal of hepatology · 2019Article
- Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.Brain, behavior, and immunity · 2019Article
- Repeated clodronate-liposome treatment results in neutrophilia and is not effective in limiting obesity-linked metabolic impairments.American journal of physiology. Endocrinology and metabolism · 2019Article
- miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice.Physiological reports · 2017Article
- Strain, Diet, and Gender Influence the Role of miR155 in Diabetes Mellitus.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Kandy T VelázquezDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.
Reilly T EnosDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.ORCID http://orcid.org/0000-0001-5571-4586
Meredith S CarsonDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.
Taryn L CranfordDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.
Jackie E BaderDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.
Alexander T SougiannisDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.
Cara PritchettDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina.
Daping FanDepartment of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina.
James A CarsonDepartment of Exercise Science, University of South Carolina, Columbia, South Carolina.
E Angela MurphyDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina Angela.Murphy@uscmed.sc.edu.
University of South Carolina · US
Funding
Use of Resveratrol to treat experimental multiple sclerosisP01AT003961 · NCCIH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, MITZI · 2007 to 2018
$14.2MCachexia in ApcMin/+ mice: The role of IL-6R01CA121249 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI CARSON, JAMES A · 2008 to 2018
$2.7MSparstolonin B as an anti-atherogenic agentR01HL116626 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FAN, DAPING · 2013 to 2017
$1.7MRegulation of Macrophages in Obesity-Enhanced Colon Cancer:Benefits of QuercetinK01AT007824 · NCCIH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MURPHY, ELIZABETH ANGELA · 2013 to 2017
$632kTargeting macrophages to reduce colorectal cancer: Impact of metabolic reprogrammingK00CA234920 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BADER, JACKIE · 2019 to 2022
$377kLinking macrophages to gut microbiota in obesity-enhanced colon cancerR21CA191966 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MURPHY, ELIZABETH ANGELA, ROBINSON, CORY MICHAEL · 2016 to 2017
$332kMacrophages in High Fat Diet Enhanced Colorectal Cancer: Regulation by miRNA-155R21CA167058 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MURPHY, ELIZABETH ANGELA · 2013 to 2014
$323kRegulation of Macrophages by miRNA-155 in Colon Cancer: Benefits of QuercetinR21CA175636 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MURPHY, ELIZABETH ANGELA · 2014 to 2015
$304kTargeting macrophages to reduce colorectal cancer: Impact of metabolic reprogrammingF99CA234920 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BADER, JACKIE · 2018 to 2018
$36kNCCIH NIH HHS K01 AT007824NCCIH NIH HHS P01 AT003961NCI NIH HHS F99 CA234920NCI NIH HHS K00 CA234920NCI NIH HHS R01 CA121249NCI NIH HHS R21 CA167058NCI NIH HHS R21 CA175636NCI NIH HHS R21 CA191966NHLBI NIH HHS R01 HL116626
Abstract
Noncoding RNAs are emerging as regulators of inflammatory and metabolic processes. There is evidence to suggest that miRNA155 (miR155) may be linked to inflammation and processes associated with adipogenesis. We examined the impact of global miRNA-155 deletion (miR155
Indexed as
AdiponectinAdipose TissueAnimalsBlood GlucoseBody WeightChemokine CCL2CollagenDiet, High-FatFibrosisInsulinMaleMAP Kinase Kinase 4MiceMice, Inbred C57BLMicroRNAsNF-kappa BAdiponectinBlood GlucoseCcl2 protein, mouseChemokine CCL2CollagenInsulinMAP Kinase Kinase 4MicroRNAsMirn155 microRNA, mouseNF-kappa BPPAR gammaRNA, MessengerTumor Necrosis Factor-alphaAdipose tissue fibrosishigh‐fat dietinflammationMicroRNA 155obesity
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.