Evidence map›Paper›PMID 28947576›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Interneuronal Network Activity at the Onset of Seizure-Like Events in Entorhinal Cortex Slices.

Laura Librizzi, Gabriele Losi, Iacopo Marcon, Michele Sessolo, Paolo Scalmani, Giorgio Carmignoto, Marco de Curtis

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. GABAFrontiers in neural circuits · 2022
    Pooled it
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  14. Downmodulation of Potassium Conductances Induces Epileptic Seizures in Cortical Network Models Via Multiple Synergistic Factors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  15. Review
  16. Synaptic Vesicle Glycoprotein 2A Knockout in Parvalbumin and Somatostatin Interneurons Drives Seizures in the Postnatal Mouse Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Laura LibrizziUnits of Epileptology and laura.librizzi@istituto-besta.it.ORCID 0000-0002-2741-4452
Gabriele LosiNeuroscience Institute, National Research Council and.ORCID 0000-0002-4931-6167
Iacopo MarconNeuroscience Institute, National Research Council and.
Michele SessoloNeuroscience Institute, National Research Council and.
Paolo ScalmaniClinical Neurophysiology, Fondazione Istituto Neurologico Carlo Besta, 20133 Milano, Italy, and.ORCID 0000-0002-3992-0926
Giorgio CarmignotoNeuroscience Institute, National Research Council and.ORCID 0000-0003-3063-6774
Marco de CurtisUnits of Epileptology and.
University of Padua · ITFondazione IRCCS Istituto Neurologico Carlo Besta · ITElectronic Product Services (Czechia) · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The onset of focal seizures in humans and in different animal models of focal epilepsy correlates with reduction of neuronal firing and enhanced interneuronal network activity. Whether this phenomenon contributes to seizure generation is still unclear. We used the

Indexed as

Action PotentialsAnimalsEntorhinal CortexFemaleGuinea PigsInhibitory Postsynaptic PotentialsInterneuronsMaleMiceMice, Inbred C57BLNerve NetOrgan Culture TechniquesSeizures4-aminopyridineextracellular potassiumGABAergic interneuronal network

Identifiers

PMID28947576
PMCPMC6596630
OpenAlexW2758730336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.