ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2017
Effect of organ donation after circulatory determination of death on number of organ transplants from donors with neurologic determination of death.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Portable Normothermic Cardiac Perfusion System in Donation After Cardiocirculatory Death: A Health Technology Assessment.Ontario health technology assessment series · 2020Pooled it
- Implementation of a controlled DCD program in Western Austria - key considerations and insights.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- A retrospective analysis of patients eligible for organ donation in adult intensive care units in Aotearoa New Zealand.Anaesthesia and intensive care · 2026Article
- Using extracorporeal membrane oxygenation in donations after cardiac death or brain death: A single-center experience and long-term outcome.Annals of gastroenterological surgery · 2024Article
- Donation after circulatory death and lung transplantation.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Review
- Anesthetic Considerations During Heart Transplantation Using Donation After Circulatory Death.Journal of cardiothoracic and vascular anesthesia · 2020Article
- When NOT to use short-term mechanical circulatory support.JTCVS open · 2020Article
- Cardiac donation after circulatory death: the heart of the matter.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020Article
- Acceptability of cardiac donation after circulatory determination of death: a survey of the Canadian public.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020Article
- Ten years of Israel's organ transplant law: is it on the right track?Israel journal of health policy research · 2018Article
- Trends in deceased organ donation in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo increase the available pool of organ donors, Ontario introduced donation after circulatory determination of death (DCD) in 2006. Other jurisdictions have reported a decrease in donations involving neurologic determination of death (NDD) after implementation of DCD, with a drop in organ yield and quality. In this study, we examined the effect of DCD on overall transplant activity in Ontario.
methodsWe examined deceased donor and organ transplant activity during 3 distinct 4-year eras: pre-DCD (2002/03 to 2005/06), early DCD (2006/07 to 2009/10) and recent DCD (2010/11 to 2013/14). We compared these donor groups by categorical characteristics.
resultsDonation increased by 57%, from 578 donors in the pre-DCD era to 905 donors in the recent DCD era, with a 21% proportion (190/905) of DCD donors in the recent DCD era. However, overall NDD donation also increased. The mean length of hospital stay before declaration for NDD was 2.7 days versus 6.0 days before withdrawal of life support and subsequent asystole in cases of DCD. The average organ yield was 3.73 with NDD donation versus 2.58 with DCD (
interpretationImplementation of DCD in Ontario led to increased transplant activity for all solid-organ recipients. There was no evidence that the use of DCD was pre-empting potential NDD donation. In contrast to groups receiving other organs, heart transplant candidates have not yet benefited from DCD.
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