Evidence map›Paper›PMID 28947540›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4

Poojitha Matta, Stacy D Sherrod, Christina C Marasco, Daniel J Moore, John A McLean, Joern-Hendrik Weitkamp

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Gut-derived T cells might cause brain injury in NEC.Nature reviews. Gastroenterology & hepatology · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Poojitha MattaDepartment of Pediatrics, Vanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN 37232.
Stacy D SherrodDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235; and.
Christina C MarascoDepartment of Physics, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0003-0324-9314
Daniel J MooreDepartment of Pediatrics, Vanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN 37232.ORCID 0000-0002-6889-9345
John A McLeanDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235; and.
Joern-Hendrik WeitkampDepartment of Pediatrics, Vanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN 37232; hendrik.weitkamp@vanderbilt.edu.
Monroe Carell Jr. Children's Hospital · USVanderbilt University · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Neurovascular Unit on a Chip: Regional Chemical Communication, Drug and Toxin ResponsesUH3TR000491 · NCATS · VANDERBILT UNIVERSITY · PI GHOSH, CHAITALI, JANIGRO, DAMIR · 2014 to 2016
$3.8M
Improving Prematurity-related Respiratory Outcomes at Vanderbilt (IMPROV)U01HL101456 · NHLBI · VANDERBILT UNIVERSITY · PI ASCHNER, JUDY LYNN · 2010 to 2014
$2.4M
Neurovascular Unit on a Chip: Chemical Communication, Drug and Toxin ResponsesUH2TR000491 · NCATS · VANDERBILT UNIVERSITY · PI JANIGRO, DAMIR, NISWENDER, KEVIN D · 2012 to 2013
$2.2M
Development of Intestinal Immune Regulation in Human InfantsK08HD061607 · NICHD · VANDERBILT UNIVERSITY · PI WEITKAMP, JOERN-HENDRIK · 2009 to 2013
$628k
NCATS NIH HHS UH2 TR000491NCATS NIH HHS UH3 TR000491NCATS NIH HHS UL1 TR000445NHLBI NIH HHS U01 HL101456NICHD NIH HHS K08 HD061607NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

Histological chorioamnionitis (HCA) is an intrauterine inflammatory condition that increases the risk for preterm birth, death, and disability because of persistent systemic and localized inflammation. The immunological mechanisms sustaining this response in the preterm newborn remain unclear. We sought to determine the consequences of HCA exposure on the fetal CD4

Indexed as

BiomarkersChorioamnionitisEnterotoxinsFemaleHumansInfant, NewbornInfant, PrematureMalePregnancyTh1 CellsBiomarkersenterotoxin B, staphylococcalEnterotoxins

Identifiers

PMID28947540
PMCPMC5659751
OpenAlexW2756549309

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.