Evidence map›Paper›PMID 28947471›Full record

ArticleAntimicrobial agents and chemotherapy2017

SPR741, an Antibiotic Adjuvant, Potentiates the

Daniel V Zurawski, Alexandria A Reinhart, Yonas A Alamneh, Michael J Pucci, Yuanzheng Si, Rania Abu-Taleb, Jonathan P Shearer, Samandra T Demons, Stuart D Tyner, Troy Lister

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 74 citations in OpenAlex.

  1. Trial
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  6. Bacterial cell envelope-targeting antibiotics.Nature reviews. Microbiology · 2026
    Review
  7. Article
  8. Broadly Defined Antibiotic Adjuvants forThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  9. Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Daniel V ZurawskiWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA daniel.v.zurawski.ctr@mail.mil.ORCID 0000-0002-7920-5601
Alexandria A ReinhartWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Yonas A AlamnehWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Michael J PucciSpero Therapeutics, Inc., Cambridge, Massachusetts, USA.
Yuanzheng SiWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Rania Abu-TalebWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Jonathan P ShearerWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Samandra T DemonsWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Stuart D TynerWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Troy ListerSpero Therapeutics, Inc., Cambridge, Massachusetts, USA.
Walter Reed Army Institute of Research · USSpero Therapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnimalsAnti-Bacterial AgentsCross InfectionDisease Models, AnimalDrug Resistance, Multiple, BacterialMiceMicrobial Sensitivity TestsPneumonia, Ventilator-AssociatedPolymyxin BProof of Concept StudyRifampinAnti-Bacterial AgentsNAB741Polymyxin BRifampinAcinetobacteranimal modelsantibacterialantibiotic adjuvantsantibiotic resistanceantibioticsESKAPE pathogensmouse modelpulmonary modelvirulent strain

Identifiers

PMID28947471
PMCPMC5700309
OpenAlexW2757377089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.