Evidence map›Paper›PMID 28947448›Full record

ArticleBMJ open2017

Risks associated with managing asthma without a preventer: urgent healthcare, poor asthma control and over-the-counter reliever use in a cross-sectional population survey.

Helen K Reddel, Rosario D Ampon, Susan M Sawyer, Matthew J Peters

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Remote monitoring in asthma: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. The use of precision medicine for asthma.Frontiers in medicine · 2025
    Article
  9. Over-the-counter short-acting βNPJ primary care respiratory medicine · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Overprescription of short-acting β2 agonists: reflections from the SABINA study in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Observational
  14. Article
  15. Development and validation of the BMQ-AIRFrontiers in pharmacology · 2024
    Article
  16. Article
  17. Over-the-counter use of short-acting beta-2 agonists: a systematic review.Journal of pharmaceutical policy and practice · 2023
    Review
  18. Clinical standards for the diagnosis and management of asthma in low- and middle-income countries.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  19. Article
  20. Over-prescription of short-acting βBMC primary care · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Helen K ReddelWoolcock Institute of Medical Research, University of Sydney, Glebe, New South Wales, Australia.
Rosario D AmponWoolcock Institute of Medical Research, University of Sydney, Glebe, New South Wales, Australia.
Susan M SawyerDepartment of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.
Matthew J PetersDepartment of Respiratory Medicine, Concord Hospital, Macquarie University, Sydney, New South Wales, Australia.
Woolcock Institute of Medical Research · AUMacquarie University · AURoyal Children's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOveruse of asthma relievers, particularly without anti-inflammatory preventers, increases asthma risks. This study aimed to identify how many reliever-only users have urgent healthcare, explore their attitudes and beliefs about asthma and its treatment, and investigate whether purchasing over-the-counter relievers was associated with worse asthma outcomes than by prescription. DESIGN AND

settingCross-sectional population-based Internet survey in Australia.

participantsOf 2686 participants ≥16 years with current asthma randomly drawn from a web-based panel, 1038 (50.7% male) used only reliever medication.

main outcome measuresUrgent asthma-related healthcare; Asthma Control Test (ACT); patient attitudes about asthma and medications; reliever purchase (with/without prescription).

resultsOf 1038 reliever-only participants, 23.3% had required urgent healthcare for asthma in the previous year, and only 36.0% had a non-urgent asthma review. Those needing urgent healthcare were more likely than those without such events to be male (56.5% vs 49.0%, p=0.003) and current smokers (29.4% vs 23.3%, p=0.009). Only 30.6% had well-controlled asthma (ACT ≥20) compared with 71.0% of those with no urgent healthcare (p<0.0001), and 20.8% used relievers regularly to prevent asthma symptoms (vs 5.5% of those without urgent healthcare). Those with urgent healthcare were more frustrated by their asthma and less happy with how they managed it, and they were less confident about their ability to manage worsening asthma, but just as likely as those without urgent healthcare to manage worsening asthma themselves rather than visit a doctor. Reliever-only users purchasing over-the-counter relievers were no more likely than those purchasing relievers by prescription to have uncontrolled asthma (35.9% vs 40.6%, p=0.23) but were less likely to have had a non-urgent asthma review.

conclusionsOne-quarter of the reliever-only population had needed urgent asthma healthcare in the previous year, demonstrating the importance of identifying such patients. Their attitudes and beliefs suggest opportunities for targeting this population in the community.

Indexed as

Attitude to HealthAdultAnti-Asthmatic AgentsAsthmaAustraliaCross-Sectional StudiesEmergency TreatmentFemaleHealth SurveysHumansMaleMiddle AgedNonprescription DrugsRisk FactorsAnti-Asthmatic AgentsNonprescription Drugsasthmahealthcare visitspreventersrelieversshort-acting β2agonists

Identifiers

PMID28947448
PMCPMC5623555
OpenAlexW2757899060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.