Evidence map›Paper›PMID 28947158›Full record

ReviewTrends in genetics : TIG2017

Stay Connected: A Germ Cell Strategy.

Kevin Lu, Lindy Jensen, Lei Lei, Yukiko M Yamashita

Abstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Early female germline development inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Female Germline Cysts in Animals: Evolution and Function.Results and problems in cell differentiation · 2024
    Review
  14. The Ancient Origin and Function of Germline Cysts.Results and problems in cell differentiation · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The dynamic duo of microtubule polymerase Mini spindles/XMAP215 and cytoplasmic dynein is essential for maintainingProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kevin LuCellular and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109, USA; Medical Scientist Training Program, University of Michigan, Ann Arbor, MI 48109, USA; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Lindy JensenLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
Lei LeiDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Yukiko M YamashitaCellular and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109, USA; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: yukikomy@umich.edu.

Funding

MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Career Training in Reproductive BiologyT32HD079342 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Suzanne M MOENTER · 2014 to 2026
$2.3M
Niche-mediated regulation of asymmetric stem cell divisionR01GM118308 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YAMASHITA, YUKIKO · 2016 to 2019
$1.2M
Nucleolar fragmentation in Drosophila germline stem cells during agingF30AG050398 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LU, KEVIN LU · 2015 to 2017
$54k
Howard Hughes Medical InstituteNIA NIH HHS F30 AG050398NICHD NIH HHS T32 HD079342NIGMS NIH HHS R01 GM118308NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

Germ cells develop as a cyst of interconnected sibling cells in a broad range of organisms in both sexes. A well-established function of intercellular connectivity is to transport cytoplasmic materials from 'nurse' cells to oocytes, a critical process for developing functional oocytes in ovaries of many species. However, there are situations where connectivity exists without a nursing mechanism, and the biological meaning of such connectivity remains obscure. In this review, we summarize current knowledge on the formation of intercellular connectivity, and discuss its meaning by visiting multiple examples of germ cell connectivity observed in evolutionarily distant species.

Indexed as

AnimalsCytoplasmFemaleGerm CellsOocytesOogenesisOvary

Identifiers

PMID28947158
PMCPMC5701820

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.