Evidence map›Paper›PMID 28946707›Full record

ArticleMolecules (Basel, Switzerland)2017

Efficacy of Bioactive Cyclic Peptides in Rheumatoid Arthritis: Translation from In Vitro to In Vivo Models.

Roger New, Michal Bogus, Gurpal S Bansal, Malgorzata Dryjska, Katarzyna Zajkowska, Michael Burnet

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Emerging Landscape ofACS pharmacology & translational science · 2024
    Review
  2. Controversy of Peptide Cyclization from Tripeptide.Molecules (Basel, Switzerland) · 2021
    Article
  3. Binding Interactions of Peptide Aptamers.Molecules (Basel, Switzerland) · 2020
    Article
  4. Peptide-Based Drugs and Drug Delivery Systems.Molecules (Basel, Switzerland) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Roger NewProxima Concepts Limited, c/o London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK. rogernew@proximaconcepts.com.
Michal BogusProxima Concepts Limited, c/o London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK. michalbogus@proximaconcepts.com.
Gurpal S BansalProxima Concepts Limited, c/o London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK. gurpal.bansal@adaptimmune.com.
Malgorzata DryjskaProxima Concepts Limited, c/o London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK. gosiadryjska@wp.pl.
Katarzyna ZajkowskaProxima Concepts Limited, c/o London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK. kz@cantab.net.
Michael BurnetSynovo GmbH, Paul Ehrlich Str. 15, 72076 Tübingen, Germany. michael.burnet@synovo.com.
Adaptimmune (United Kingdom) · GBBlue Ventures · GBSynovo (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using a novel drug discovery technology reported in previous issues of this journal cyclic peptides have been created which are able to down-regulate secretion of inflammatory cytokines

Indexed as

AnimalsArthritis, RheumatoidCell LineDisease Models, AnimalInterleukin-6MicePeptides, CyclicSynovial MembraneTumor Necrosis Factor-alphaInterleukin-6Peptides, CyclicTumor Necrosis Factor-alphacyclic peptideinterleukin 6lipoamino acidrheumatoid arthritisTNF

Identifiers

PMID28946707
PMCPMC6151468
OpenAlexW2756690088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.