Evidence map›Paper›PMID 28946693›Full record

ArticleViruses2017

Inference of a Geminivirus-Host Protein-Protein Interaction Network through Affinity Purification and Mass Spectrometry Analysis.

Liping Wang, Xue Ding, Jiajing Xiao, Tamara Jiménez-Gόngora, Renyi Liu, Rosa Lozano-Durán

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liping WangShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai 201602, China. wlp@sibs.ac.cn.
Xue DingShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai 201602, China. dingxue@sibs.ac.cn.
Jiajing XiaoShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai 201602, China. jjxiao@sibs.ac.cn.ORCID 0000-0002-0268-2944
Tamara Jiménez-GόngoraShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai 201602, China. tamara@sibs.ac.cn.ORCID 0000-0001-9831-251X
Renyi LiuShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai 201602, China. lozano-duran@sibs.ac.cn.ORCID 0000-0001-7348-8842
Rosa Lozano-DuránShanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai 201602, China. ryliu@sibs.ac.cn.
Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses reshape the intracellular environment of their hosts, largely through protein-protein interactions, to co-opt processes necessary for viral infection and interference with antiviral defences. Due to genome size constraints and the concomitant limited coding capacity of viruses, viral proteins are generally multifunctional and have evolved to target diverse host proteins. Inference of the virus-host interaction network can be instrumental for understanding how viruses manipulate the host machinery and how re-wiring of specific pathways can contribute to disease. Here, we use affinity purification and mass spectrometry analysis (AP-MS) to define the global landscape of interactions between the geminivirus

Indexed as

Host-Pathogen InteractionsBegomovirusChromatography, AffinityEvolution, MolecularMass SpectrometryNicotianaPlant DiseasesPlant ProteinsProtein Interaction MapsSolanum tuberosumViral ProteinsPlant ProteinsViral Proteinsbroad-spectrum resistanceGeminivirushosthubsnetworkNicotiana benthamianapathogensplantprotein-protein interactionsTYLCV

Identifiers

PMID28946693
PMCPMC5691627
OpenAlexW2757055729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.