Evidence map›Paper›PMID 28945950›Full record

ReviewLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society2017

Complexity and function of natural killer T cells with potential application to hepatic transplant survival.

Randle Ware, Vipin Kumar

Open access · bronzeAbstract readReview
In one paragraph

Review in Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. The role of natural killer T cells in liver transplantation.Frontiers in cell and developmental biology · 2023
    Review
  3. Immune response associated with ischemia and reperfusion injury during organ transplantation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Randle WareLaboratory of Immune Regulation, Department of Medicine, University of California, San Diego, La Jolla, CA.
Vipin KumarLaboratory of Immune Regulation, Department of Medicine, University of California, San Diego, La Jolla, CA.
University of California, San Diego · US

Funding

Sulfatide-reactive type II NKT cells: repertoire and functionR01CA100660 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUMAR, VIPIN · 2004 to 2014
$3.5M
Interplay Among NKT Cell Subsets in Alcoholic Liver DiseaseR01AA020864 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUMAR, VIPIN · 2012 to 2016
$1.8M
NCI NIH HHS R01 CA100660NIAAA NIH HHS R01 AA020864
6 · The paper itself

Abstract

One of the major innate-like lymphocyte populations enriched in the liver consists of natural killer T (NKT) cells, which recognize self and foreign lipid antigens presented by the nonpolymorphic class I major histocompatibility complex-like molecule CD1d. NKT cells express natural killer cell markers as well as T cell receptors (TCRs) and can be classified into 2 categories: type I NKT cells use a semi-invariant TCR, whereas type II NKT cells express diverse but still limited TCRs. An emerging body of evidence points to their opposing roles in inflammation, including ischemia/reperfusion injury. Improved understanding of their roles in experimental models as well as in humans and the means by which their function can be manipulated may provide therapeutic benefit in liver diseases and in organ transplantation. Liver Transplantation 23 1589-1592 2017 AASLD.

Indexed as

AnimalsAntigen PresentationAntigens, CD1dGraft SurvivalHumansLiverLiver DiseasesLiver TransplantationMiceNatural Killer T-CellsReceptors, Antigen, T-CellReperfusion InjuryAntigens, CD1dReceptors, Antigen, T-Cell

Identifiers

PMID28945950
PMCPMC6075735
OpenAlexW2802649606

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.