Evidence map›Paper›PMID 28945943›Full record

ArticleEnvironmental toxicology and chemistry2017

The Role of Epigenomics in Aquatic Toxicology.

Susanne M Brander, Adam D Biales, Richard E Connon

Abstract read
In one paragraph

Article in Environmental toxicology and chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Susanne M BranderDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon, USA.
Adam D BialesNational Exposure Research Laboratory, US Environmental Protection Agency, Cincinnati, Ohio.
Richard E ConnonDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, California, USA.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Over the past decade, the field of molecular biology has rapidly incorporated epigenetic studies to evaluate organism-environment interactions that can result in chronic effects. Such responses arise from early life stage stress, the utilization of genetic information over an individual's life time, and transgenerational inheritance. Knowledge of epigenetic mechanisms provides the potential for a comprehensive evaluation of multigenerational and heritable effects from environmental stressors, such as contaminants. Focused studies have provided a greater understanding of how many responses to environmental stressors are driven by epigenetic modifiers. We discuss the promise of epigenetics and suggest future research directions within the field of aquatic toxicology, with a particular focus on the potential for identifying key heritable marks with consequential impacts at the organism and population levels. Environ Toxicol Chem 2017;36:2565-2573. © 2017 SETAC.

Indexed as

EpigenomicsAnimalsAquatic OrganismsBiological EvolutionChromatinDNA MethylationEndocrine DisruptorsGerm CellsHistonesProtein Processing, Post-TranslationalRNA, UntranslatedWater Pollutants, ChemicalChromatinEndocrine DisruptorsHistonesRNA, UntranslatedWater Pollutants, ChemicalAquatic toxicologyContaminantsEcotoxicogenomicsEpigeneticsStressors

Identifiers

PMID28945943
PMCPMC6145079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.