Evidence map›Paper›PMID 28945495›Full record

ArticleOphthalmic epidemiology2018

Validity of code based algorithms to identify primary open angle glaucoma (POAG) in Veterans Affairs (VA) administrative databases.

K S Biggerstaff, B J Frankfort, S Orengo-Nania, J Garcia, E Chiao, J R Kramer, D White

Abstract readValidation Study
In one paragraph

Article in Ophthalmic epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Article
  6. Association of Age of Menopause and Glaucoma Diagnosis in Female Veterans.Investigative ophthalmology & visual science · 2024
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  12. Gout and open-angle glaucoma risk in a veteran population.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

K S Biggerstaffa Houston Center for Innovations in Quality, Effectiveness and Safety , Michael E. DeBakeyVeterans Affairs Medical Center , Houston , TX , USA.
B J Frankfortc Department of Ophthalmology , Baylor College of Medicine , Houston , TX , USA.
S Orengo-Naniab Eye Care Line , Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
J Garciad Division of Diabetes, Endocrinology and Metabolism, MCL, Center for Translational Research on Inflammatory Diseases , Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine , Houston , TX , USA.
E Chiaoa Houston Center for Innovations in Quality, Effectiveness and Safety , Michael E. DeBakeyVeterans Affairs Medical Center , Houston , TX , USA.
J R Kramera Houston Center for Innovations in Quality, Effectiveness and Safety , Michael E. DeBakeyVeterans Affairs Medical Center , Houston , TX , USA.
D Whitea Houston Center for Innovations in Quality, Effectiveness and Safety , Michael E. DeBakeyVeterans Affairs Medical Center , Houston , TX , USA.

Funding

Androgen Receptor Pathway and Risk of Hepatic Fibrosis in Hepatitis CR03DK095082 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI WHITE, DONNA LORRAINE · 2013 to 2014
$153k
Sex hormones and HCV-related liver disease progressionI01CX001430 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI WHITE, DONNA LORRAINE · 2017 to 2021
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CSRD VA I01 CX001430NIDDK NIH HHS L30 DK089939NIDDK NIH HHS R03 DK095082
6 · The paper itself

Abstract

purposeThe validity of the International Classification of Diseases, 9th revision, Clinical Modification (ICD-9) code for primary open angle glaucoma (POAG) in the Department of Veterans Affairs (VA) electronic medical record has not been examined. We determined the accuracy of the ICD-9 code for POAG and developed diagnostic algorithms for the detection of POAG.

methodsWe conducted a retrospective study of abstracted data from the Michael E. DeBakey VA Medical Center's medical records of 334 unique patients with at least one visit to the Eye Clinic between 1999 and 2013. Algorithms were developed to validly identify POAG using ICD-9 codes and pharmacy data. The positive predictive value (PPV), negative predictive value (NPV), sensitivity, specificity and percent agreement of the various algorithms were calculated.

resultsFor the ICD-9 code 365.1x, the PPV was 65.9%, NPV was 95.2%, sensitivity was 100%, specificity was 82.6%, and percent agreement was 87.8%. The algorithm with the highest PPV was 76.3%, using pharmacy data in conjunction with two or more ICD-9 codes for POAG, but this algorithm also had the lowest NPV at 88.2%.

conclusionsVarious algorithms for identifying POAG in the VA administrative databases have variable validity. Depending on the type of research being done, the ICD-9 code 365.1x can be used for epidemiologic or health services database research.

Indexed as

AlgorithmsAgedDatabases, FactualElectronic Health RecordsFemaleGlaucoma, Open-AngleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesROC CurveUnited StatesUnited States Department of Veterans AffairsVeteransadministrative databaseGlaucomavalidationveterans

Identifiers

PMID28945495
PMCPMC7185901

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.