Evidence map›Paper›PMID 28945206›Full record

ArticleJournal of pediatric gastroenterology and nutrition2017

Psychological Distress and Quality of Life in Pediatric Crohn Disease: Impact of Pain and Disease State.

Robyn Lewis Claar, Miranda A L van Tilburg, Bisher Abdullah, Shelby Langer, Dalia Sherif, William E Whitehead, Douglas A Drossman, Rona L Levy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Orofacial granulomatosis: a questionnaire study among Norwegian dental clinicians.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020
    Article
  9. Review
  10. Article
  11. The Impact of Inflammatory Bowel Disease in Canada 2018: Children and Adolescents with IBD.Journal of the Canadian Association of Gastroenterology · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Robyn Lewis Claar*Department of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC†Department of Clinical Research, Campbell University College of Pharmacy and Health Science, Buies Creek, NC‡Prime Health Clinic, Tacoma, WA§College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ¶Multicare Institute for Research and Innovation, Tacoma, WA||School of Social Work, University of Washington, Seattle, WA.
Miranda A L van Tilburg
Bisher Abdullah
Shelby Langer
Dalia Sherif
William E Whitehead
Douglas A Drossman
Rona L Levy
University of North Carolina at Chapel Hill · USArizona State University · USMultiCare Health System · USPublic Risk Management Association · USUniversity of Washington · US

Funding

Parent training to address pediatric functional abdominal painR01HD036069 · NICHD · UNIVERSITY OF WASHINGTON · PI LEVY, RONA L. · 1999 to 2015
$6.4M
Psychosocial Intervention for Children with IBDR01HD050345 · NICHD · UNIVERSITY OF WASHINGTON · PI LEVY, RONA L. · 2007 to 2010
$2.0M
NICHD NIH HHS R01 HD036069NICHD NIH HHS R01 HD050345
6 · The paper itself

Abstract

objectivesFor patients with Crohn disease (CD), symptom reporting may not coincide with disease state; patients in remission may continue to report symptoms and pain, whereas other patients may be symptom-free despite a flare. This phenomenon has been documented in adults but only recently assessed in pediatric patients. The present study assessed the role of pain reporting and disease state in pediatric patients with CD in understanding psychological distress and quality of life.

methodsParticipants included 116 children and adolescents ages 8 to 18 years with CD who completed self-report questionnaires assessing pain, disease symptoms, depression, anxiety, functional disability, and quality of life. Physicians completed the Pediatric Crohn's Disease Activity Index to assess disease activity (scores ≤10 = remission, scores >10 = flare).

resultsApproximately two thirds of participants reported pain concordant with disease state. For patients in remission, those with pain experienced significantly increased disability and decreased quality of life compared to patients in remission without pain. For patients in a flare, those without pain experienced significantly decreased disability and depressive symptoms, and improved quality of life compared to patients in a flare with pain.

conclusionsFor pediatric patients with CD, report of pain, while in remission or a flare, is associated with increased disability and reduced quality of life. Although levels of depression did not differ by disease state, depressive symptoms did differ by pain report (presence or absence) for those in a flare. Pain reporting in CD appears to be associated with both physical and psychological state and should be assessed regardless of disease activity.

Indexed as

AdolescentChildCrohn DiseaseFemaleHumansMalePainQuality of LifeSelf ReportStress, PsychologicalSurveys and Questionnaires

Identifiers

PMID28945206
PMCPMC5637279
OpenAlexW2590831482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.