Evidence map›Paper›PMID 28945181›Full record

ArticlePsychiatric services (Washington, D.C.)2018

Modeling the Cost-Effectiveness of Interventions to Reduce Suicide Risk Among Hospital Emergency Department Patients.

Peter Denchev, Jane L Pearson, Michael H Allen, Cynthia A Claassen, Glenn W Currier, Douglas F Zatzick, Michael Schoenbaum

Abstract read
In one paragraph

Article in Psychiatric services (Washington, D.C.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Artificial Intelligence and Suicide Prevention: A Systematic Review of Machine Learning Investigations.International journal of environmental research and public health · 2020
    Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cost-effectiveness of implementing a suicide prediction tool (OxMIS) in severe mental illness: Economic modeling study.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter DenchevAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.
Jane L PearsonAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.
Michael H AllenAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.
Cynthia A ClaassenAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.
Glenn W CurrierAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.
Douglas F ZatzickAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.
Michael SchoenbaumAt the time of this research, Dr. Denchev was with the Office of Science Policy, Planning and Communication, National Institute of Mental Health (NIMH), Bethesda, Maryland. Dr. Pearson and Dr. Schoenbaum are with the Division of Services and Intervention Research, NIMH, Bethesda. Dr. Allen is with the Department of Psychiatry, University of Colorado Denver School of Medicine, Aurora, and with Rocky Mountain Crisis Partners, Denver. Dr. Claassen is with the Department of Psychiatry, University of North Texas Health Science Center, Fort Worth. Dr. Currier is with the Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa. Dr. Zatzick is with the Department of Psychiatry and Behavioral Sciences, University of Washington and Harborview Medical Center, Seattle.

Funding

Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

objectiveThis study estimated the expected cost-effectiveness and population impact of outpatient interventions to reduce suicide risk among patients presenting to general hospital emergency departments (EDs), compared with usual care. Several such interventions have been found efficacious, but none is yet widespread, and the cost-effectiveness of population-based implementation is unknown.

methodsModeled cost-effectiveness analysis compared three ED-initiated suicide prevention interventions previously found to be efficacious-follow-up via postcards or caring letters, follow-up via telephone outreach, and suicide-focused cognitive-behavioral therapy (CBT)-with usual care. Primary outcomes were treatment costs, suicides, and life-years saved, evaluated over the year after the index ED visit.

resultsCompared with usual care, adding postcards improved outcomes and reduced costs. Adding telephone outreach and suicide-focused CBT, respectively, improved outcomes at a mean incremental cost of $4,300 and $18,800 per life-year saved, respectively. Monte Carlo simulation (1,000 repetitions) revealed the chance of incremental cost-effectiveness to be a certainty for all three interventions, assuming societal willingness to pay ≥$50,000 per life-year. These main findings were robust to various sensitivity analyses, including conservative assumptions about effect size and incremental costs. Population impact was limited by low sensitivity of detecting ED patients' suicide risk, and health care delivery inefficiencies.

conclusionsThe highly favorable cost-effectiveness found for each outpatient intervention provides a strong basis for widespread implementation of any or all of the interventions. The estimated population benefits of doing so would be enhanced by increasing the sensitivity of suicide risk detection among individuals presenting to general hospital EDs.

Indexed as

AftercareCognitive Behavioral TherapyEmergency Service, HospitalOutcome and Process Assessment, Health CareSuicideSuicide PreventionAdultCost-Benefit AnalysisHumansModels, StatisticalOutpatientsPostcards as TopicTelephoneCost-effectiveness analysisEmergency psychiatrySuicide & self-destructive behavior

Identifiers

PMID28945181
PMCPMC5750130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.