Evidence map›Paper›PMID 28945100›Full record

ArticleEuropean journal of preventive cardiology2017

Clinical characteristics of HIV-infected patients with adjudicated heart failure.

Alexandra B Steverson, Anna E Pawlowski, Daniel Schneider, Prasanth Nannapaneni, Jes M Sanders, Chad J Achenbach, Sanjiv J Shah, Donald M Lloyd-Jones, Matthew J Feinstein

Open access · greenAbstract read
In one paragraph

Article in European journal of preventive cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Adjudicated Heart Failure in HIV-Infected and Uninfected Men and Women.Journal of the American Heart Association · 2018
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alexandra B SteversonFeinberg School of Medicine, Northwestern University, USA.
Anna E PawlowskiFeinberg School of Medicine, Northwestern University, USA.
Daniel SchneiderFeinberg School of Medicine, Northwestern University, USA.
Prasanth NannapaneniFeinberg School of Medicine, Northwestern University, USA.
Jes M SandersFeinberg School of Medicine, Northwestern University, USA.
Chad J AchenbachFeinberg School of Medicine, Northwestern University, USA.
Sanjiv J ShahFeinberg School of Medicine, Northwestern University, USA.
Donald M Lloyd-JonesFeinberg School of Medicine, Northwestern University, USA.
Matthew J FeinsteinFeinberg School of Medicine, Northwestern University, USA.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Mohamed Abdel Mohsen · 2015 to 2026
$38.4M
NCATS NIH HHS UL1 TR001422NIAID NIH HHS P30 AI117943
6 · The paper itself

Abstract

Aims HIV-infected persons may have elevated risks for heart failure, but factors associated with heart failure in the modern era of HIV therapy are insufficiently understood. Despite substantial disagreement between physician-adjudicated heart failure and heart failure diagnosis codes, few studies of HIV cohorts have evaluated adjudicated heart failure. We evaluated associations of HIV viremia, immunosuppression, and cardiovascular risk factors with physician-adjudicated heart failure. Methods and results We analyzed clinical characteristics associated with heart failure in a cohort of 5041 HIV-infected patients receiving care at an urban hospital system between 2000 and 2016. We also evaluated characteristics of HIV-infected patients who screened negative for heart failure, screened positive for possible heart failure but did not have heart failure after adjudication, and had adjudicated heart failure. HIV-infected patients with heart failure ( N = 216) were older and more likely to be black, hypertensive, and have diabetes than HIV-infected patients without heart failure; heart failure with reduced ejection fraction was more common than heart failure with preserved ejection fraction. In our primary analyses restricted to HIV-infected patients whose heart failure diagnoses did not precede their HIV diagnoses ( N = 149), peak HIV viral load ≥100,000 copies/mL (odds ratio (OR) 2.12, 1.28-3.52) and nadir CD4 T-cell count <200 cells/mm

Indexed as

HIVRisk AssessmentCause of DeathCD4 Lymphocyte CountDiagnostic ImagingFemaleFollow-Up StudiesHeart FailureHIV InfectionsHospitals, UrbanHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk Factorsadjudicationelectronic cohortHeart failureHIV

Identifiers

PMID28945100
PMCPMC5800758
OpenAlexW2760417625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.