ArticleMolecular medicine reports2017
microRNA‑372 inhibits proliferation and induces apoptosis in human breast cancer cells by directly targeting E2F1.
Article in Molecular medicine reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- A comprehensive review on apoptotic miRNAs and antagomiRs in breast cancer: Enhancing radio sensitization.Genes & diseases · 2026Review
- Non-coding RNAs, a double-edged sword in breast cancer prognosis.Cancer cell international · 2025Review
- E2F1 activates breast stromal fibroblasts and promotes their paracrine pro-carcinogenic effects.Scientific reports · 2025Article
- Profiles of Circulating Exosomal miRNA in Patients with SAPHO Patients by High-Throughput Sequencing.Combinatorial chemistry & high throughput screening · 2025Article
- Exploring the intricate relationship between miRNA dysregulation and breast cancer development: insights into the impact of environmental chemicals.Frontiers in immunology · 2024Review
- Feedback Modulation between Human INO80 Chromatin Remodeling Complex and miR-372 in HCT116 Cells.International journal of molecular sciences · 2023Article
- Review
- ST08 Altered NF-κB Pathway in Breast Cancer CellsFrontiers in oncology · 2022Article
- MiR-372-3p Functions as a Tumor Suppressor in Colon Cancer by Targeting MAP3K2.Frontiers in genetics · 2022Article
- MicroRNA-1298-5p inhibits the tumorigenesis of breast cancer by targeting E2F1.Oncology letters · 2021Article
- Effects of FER1L4-miR-106a-5p/miR-372-5p-E2F1 regulatory axis on drug resistance in liver cancer chemotherapy.Molecular therapy. Nucleic acids · 2021Article
- HIGD-Driven Regulation of CytochromeCells · 2020Review
- Reciprocal regulation of miR-1205 and E2F1 modulates progression of laryngeal squamous cell carcinoma.Cell death & disease · 2019Article
- RETRACTED: Comprehensive Analysis of the Expression and Prognosis for E2Fs in Human Breast CancerMolecular therapy : the journal of the American Society of Gene Therapy · 2019Article
- FER1L4/miR-372/E2F1 works as a ceRNA system to regulate the proliferation and cell cycle of glioma cells.Journal of cellular and molecular medicine · 2019Article
- Jieduan-Niwan Formula Reduces Liver Apoptosis in a Rat Model of Acute-on-Chronic Liver Failure by Regulating the E2F1-Mediated Intrinsic Apoptosis Pathway.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- MicroRNA Expression Changes in Women with Breast Cancer Stratified by DNA Repair Capacity Levels.Journal of oncology · 2019Article
- Expressions and prognostic values of theCancer management and research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is the most prevalent cancer and the leading cause of cancer‑associated mortalities among women worldwide today. Accumulating evidence suggested that miR‑372 may serve important roles in the initiation and development of various human cancers. However, the role of miR‑372 in breast cancer remains unknown. The present study demonstrated that the expression level of miR‑372 in human breast cancer tissues and cell lines is significantly reduced compared with normal breast tissues cell lines. Furthermore, results of functional assays indicated that miR‑372 inhibits cell proliferation and induces apoptosis in the MCF‑7 human breast cancer cell line. E2F1 was identified as a direct functional target of miR‑372 in breast cancer. In conclusion, the findings revealed that miR‑372 may have the potential to act as a novel molecule for the diagnosis and therapy of patients with breast cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.