Evidence map›Paper›PMID 28944582›Full record

ArticleJournal of cachexia, sarcopenia and muscle2017

Myopenia and precision (P4) medicine.

John E Morley, Stefan D Anker

Abstract readEditorial
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Editorial: Resilience And Successful Aging.The journal of nutrition, health & aging · 2022
    Article
  6. Article
  7. Review
  8. Editorial: The Future of Geriatrics.The journal of nutrition, health & aging · 2020
    Article
  9. Review
  10. Article
  11. Review
  12. Editorial: Vitamin D: Does the Emperor Have No Clothes?The journal of nutrition, health & aging · 2019
    Article
  13. Senolytics: The Modern Snake Oil?The journal of nutrition, health & aging · 2019
    Article
  14. Editorial: Population Health and Aging.The journal of nutrition, health & aging · 2019
    Article
  15. Treatment of sarcopenia: the road to the future.Journal of cachexia, sarcopenia and muscle · 2018
    Article
  16. Article
  17. Article
  18. Editorial: Dysphagia, Dementia and Frailty.The journal of nutrition, health & aging · 2018
    Article
  19. Editorial: Frailty, Comorbidity, and COPD.The journal of nutrition, health & aging · 2018
    Article
  20. Myopenia and precision (P4) medicine.Journal of cachexia, sarcopenia and muscle · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John E MorleyDivision of Geriatric Medicine, Saint Louis University School of Medicine, 1402 S. Grand Blvd., M238, St. Louis, MO, 63104, USA.
Stefan D AnkerDivision of Innovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Centre Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision (P4) medicine represents a new medical paradigm that focuses on Personalized, Predictive, Preventive and Participatory approaches. The P4 paradigm is particularly appropriate for moving the care of persons with myopenia forward. Muscular dystrophies are clearly a set of genetically different diseases where genomics are the basis of diagnosis, and genetic modulation via DNA, oligonucleotides and clustered regularly interspaced short palendronic repeats hold great potential for a cure. The utility of personalized genomics for sarcopenia coupled with utilizing a predictive approach for the diagnosis with early preventive strategies is a key to improving sarcopenic outcomes. The importance of understanding different levels of patient enthusiasm and different responses to exercise should guide the participatory phase of sarcopenic treatment. In the case of cachexia, understanding the effects of the different therapies now available through the P4 approach on muscle wasting is a key to management strategies.

Indexed as

Precision MedicineAnimalsCachexiaHumansMuscular AtrophySarcopeniaMuscular dystrophyMyopeniaPersonalized medicinePrecision medicine

Identifiers

PMID28944582
PMCPMC5700444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.