Evidence map›Paper›PMID 28944421›Full record

ArticleClinical rheumatology2018

Metabolic abnormalities in rheumatoid arthritis patients with comorbid diabetes mellitus.

Xing Zhen Liu, Ying Gao, Jie Fan, Xia Xu, Ju Zhang, Jie Gao, Wei Wan, Dong Bao Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. A systematic review and meta-analysis of circulating adhesion molecules in rheumatoid arthritis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Pooled it
  3. Hypertension in connective tissue disease.Journal of human hypertension · 2024
    Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xing Zhen LiuDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China.
Ying GaoDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China.
Jie FanArmy Convalescence Area, Hangzhou Sanatorium of People's Liberation Army, Hangzhou, China.
Xia XuDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China.
Ju ZhangDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China.
Jie GaoDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China.
Wei WanDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China.
Dong Bao ZhaoDepartment of Rheumatology and immunology, Changhai Hospital, The Second Military Medical University, No. 168, Changhai Road, Yangpu District, Shanghai, 200433, China. dongbaozhao@163.com.
Second Military Medical University · CNChanghai Hospital · CN

Funding

National Natural Science Foundation of China 81471607National Natural Science Foundation of China 81671595
6 · The paper itself

Abstract

The metabolic characteristics of rheumatoid arthritis (RA) or diabetes mellitus (DM) have been studied, but the metabolic abnormalities of RA patients complicated with DM are not completely understood. Therefore, we recruited RA patients with DM to investigate the metabolic abnormalities in these patients. We collected data of RA patients with DM and age- and sex-matched RA and DM patients from Changhai Hospital's electronic medical record system. Data of demographically matched healthy controls were also collected from the health management system of the Hangzhou Sanatorium of People's Liberation Army. Blood pressure, uric acid, glucose, and lipid levels were compared. The clinical data of RA with DM (n = 104), DM (n = 100), and RA (n = 100) patients and healthy controls (n = 100) were collected and compared. RA patients with DM had higher blood pressure and lower high-density lipoprotein cholesterol levels than the other three groups, a higher triglycerides (TG) level than healthy controls and RA patients, and a lower TG level than DM patients. RA patients with DM exhibited a relatively high proportion of metabolic abnormalities based on existing standards. Our study examined metabolic abnormalities in RA patients with DM for the first time, and our results suggest that clinicians should pay more attention to the metabolic abnormalities of RA patients with DM.

Indexed as

AgedArthritis, RheumatoidBlood PressureCholesterolDiabetes Mellitus, Type 2DyslipidemiasFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTriglyceridesCholesterolTriglyceridesCardiovascular diseaseDiabetesDyslipidemiaRheumatoid arthritis

Identifiers

PMID28944421
OpenAlexW2758936383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.