Evidence map›Paper›PMID 28944413›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017

Longer-term Baerveldt to Trabectome glaucoma surgery comparison using propensity score matching.

Tigran Kostanyan, Tarek Shazly, Kevin B Kaplowitz, Steven Z Wang, Sushma Kola, Eric N Brown, Nils A Loewen

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Visual Function After Schlemm's Canal-Based MIGS.Journal of clinical medicine · 2025
    Review
  2. Review
  3. Article
  4. Exact matching of trabectome-mediated ab interno trabeculectomy to conventional trabeculectomy with mitomycin C followed for 2 years.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  5. Article
  6. Impact of same-session trabectome surgery on Ahmed glaucoma valve outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tigran KostanyanDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Tarek ShazlyDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Kevin B KaplowitzDepartment of Ophthalmology, VA Loma Linda, Loma Linda University, Loma Linda, CA, USA.
Steven Z WangDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Sushma KolaDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Eric N BrownDepartment of Ophthalmology, Vanderbilt University Medical Center, Nashville, TN, USA.
Nils A LoewenDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA. loewen.nils@gmail.com.ORCID http://orcid.org/0000-0001-7167-1213
University of Pittsburgh · USLoma Linda University · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo apply propensity score matching to compare Baerveldt glaucoma drainage implant (BGI) to Trabectome-mediated ab interno trabeculectomy (AIT). Recent data suggests that AIT can produce results similar to BGI which is traditionally reserved for more severe glaucoma.

methodsBGI and AIT patients with at least 1 year of follow-up were included. The primary outcome measures were intraocular pressure (IOP), number of glaucoma medications, and a Glaucoma Index (GI) score. GI reflected glaucoma severity based on visual field, the number of preoperative medications, and preoperative IOP. Score matching used a genetic algorithm consisting of age, gender, type of glaucoma, concurrent phacoemulsification, baseline number of medications, and baseline IOP. Patients with neovascular glaucoma, with prior glaucoma surgery, or without a close match were excluded.

resultsOf 353 patients, 30 AIT patients were matched to 29 BGI patients. Baseline characteristics including, IOP, the number of glaucoma medications, type of glaucoma, the degree of VF loss and GI were not significantly different between AIT and BGI. BGI had a preoperative IOP of 21.6 ± 6.3 mmHg compared to 21.5 ± 7.4 for AIT on 2.8 ± 1.1 medications and 2.5 ± 2.3 respectively. At 30 months, the mean IOP was 15.0 ± 3.9 mmHg for AIT versus 15.0 ± 5.7 mmHg for BGI (p > 0.05), while the number of drops was 1.5 ± 1.3 for AIT (change: p = 0.001) versus 2.4 ± 1.2 for BGI (change: p = 0.17; AIT vs BGI: 0.007). Success, defined as IOP < 21 mmHg, < 20% reduction and no reoperation, was achieved at 1 year in 56% of AIT versus 55% of BGI (p > 0.05) and 50% versus 52% at 2.5 years.

conclusionsA propensity score matched comparison of AIT and BGI demonstrated a similar IOP reduction through 1 year. AIT required fewer medications.

Indexed as

Glaucoma Drainage ImplantsIntraocular PressurePropensity ScoreAgedFemaleFollow-Up StudiesGlaucomaHumansMaleRetrospective StudiesTime FactorsTrabeculectomyTreatment OutcomeVisual FieldsAITBaerveldtGlaucomaMinimally invasive glaucoma surgeryPOAGTrabectome

Identifiers

PMID28944413
OpenAlexW2612371429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.