ArticleTemperature (Austin, Tex.)2017
The effect of passive heating on heat shock protein 70 and interleukin-6: A possible treatment tool for metabolic diseases?
Article in Temperature (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- The effects of hot-water immersion on cardiovascular and cardiorespiratory health of healthy adults: A systematic review and meta-analysis.Physiological reports · 2026Pooled it
- Effects of Heat Exposure on Kynurenine Pathway Metabolism-Comparison Between Exertional and Exogenous Heating of the Human Body.Acta physiologica (Oxford, England) · 2025Trial
- A Single Sauna Session Does Not Improve Postprandial Blood Glucose Handling in Individuals with Type 2 Diabetes Mellitus: A Cross-Over, Randomized, Controlled Trial.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2024Trial
- Passive heat therapy protects against endothelial cell hypoxia-reoxygenation via effects of elevations in temperature and circulating factors.The Journal of physiology · 2018Trial
- A peripheral perspective on brain health: vascular and skeletal muscle contributions.American journal of physiology. Heart and circulatory physiology · 2026Review
- Whole-blood transcriptomic response to whole-body hyperthermia in participants with major depressive disorder.Brain, behavior, & immunity - health · 2026Article
- Passive heat therapy is feasible but does not affect cardiometabolic health outcomes in persons with spinal cord injury - a pilot study.Experimental physiology · 2026Article
- The effect of repeated hot water immersion on microvascular function, glycaemic control and inflammation in White European and South Asian males.Experimental physiology · 2026Article
- Heat Therapy: Targeting Health, Disease, and Disability.Comprehensive Physiology · 2026Review
- Applying thermal therapy: Comparison of different commercially available heating devices to increase muscle temperature.Experimental physiology · 2026Article
- Diabetes, Protein Misfolding, and Heat Stress: Molecular Insights and Translational Perspectives.TH open : companion journal to thrombosis and haemostasis · 2026Review
- Heat thermotherapy to improve cardiovascular function and cardiometabolic health: A systematic review and meta-analysis.Experimental physiology · 2025Article
- Comparison of thermoregulatory, cardiovascular, and immune responses to different passive heat therapy modalities.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Muscle temperature increases during a single far infrared sauna session without changes in intestinal temperature.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole-body passive hyperthermia in healthy humans.Experimental physiology · 2025Article
- Effects of Fish Oil with Heat Treatment on Obesity, Inflammation, and Gut Microbiota in Ovariectomized Mice.Nutrients · 2025Article
- Facial cooling improves thermal perceptions and maintains the interleukin-6 response during passive heating: A sex comparison.Temperature (Austin, Tex.) · 2025Article
- Hot water immersion is associated with higher thermal comfort than dry passive heating for a similar rise in rectal temperature and plasma interleukin-6 concentration.European journal of applied physiology · 2024Article
- The multifaceted benefits of passive heat therapies for extending the healthspan: A comprehensive review with a focus on Finnish sauna.Temperature (Austin, Tex.) · 2024Review
- Maintenance of homeostasis by TLR4 ligands.Frontiers in immunology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing physical activity remains the most widely publicized way of improving health and wellbeing. However, in populations that benefit most from exercise (EX), adherence is often poor and alternatives to EX are important to bring about health improvements. Recent work suggests a role for passive heating (PH) and heat shock proteins (HSP) in improving cardio-metabolic health. The aim of this study was to investigate the expression of HSP70 and interleukin-6 in response to either EX or PH and the subsequent effect on glucose control. Fourteen males volunteered and were categorized lean (BMI 23.5 ± 2.2 kg·m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.