Evidence map›Paper›PMID 28944236›Full record

ArticleMolecular genetics & genomic medicine2017

The angiotensin-converting enzyme insertion/deletion polymorphism rs4340 associates with habitual physical activity among European American adults.

Michael Bruneau, Theodore J Angelopoulos, Paul Gordon, Niall Moyna, Paul Visich, Robert Zoeller, Rick Seip, Stephen Bilbie, Paul Thompson, Joseph Devaney and 3 more

Abstract read
In one paragraph

Article in Molecular genetics & genomic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genetic variants related to physical activity or sedentary behaviour: a systematic review.The international journal of behavioral nutrition and physical activity · 2021
    Pooled it
  2. Molecular Portrait of an Athlete.Diagnostics (Basel, Switzerland) · 2021
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michael BruneauDrexel UniversityPhiladelphiaPennsylvania.ORCID 0000-0002-4588-1468
Theodore J AngelopoulosEmory & Henry CollegeEmoryVirginia.
Paul GordonBaylor UniversityWacoTexas.
Niall MoynaDublin City UniversityDublinIreland.
Paul VisichUniversity of New EnglandBiddefordMaine.
Robert ZoellerFlorida Atlantic UniversityBoca RatonFlorida.
Rick SeipHartford HealthcareHartfordConnecticut.
Stephen BilbieHartford HealthcareHartfordConnecticut.
Paul ThompsonHartford HealthcareHartfordConnecticut.
Joseph DevaneyChildren's National Medical CenterWashingtonDistrict of Columbia.
Heather Gordish-DressmanChildren's National Medical CenterWashingtonDistrict of Columbia.
Eric HoffmanCooperative International Neuromuscular Research GroupWashingtonDistrict of Columbia.
Linda S PescatelloUniversity of ConnecticutStorrsConnecticut.

Funding

Functional SNP's Assoc with Human Muscle Size &StrengthR01NS040606 · NINDS · CHILDREN'S RESEARCH INSTITUTE · PI HOFFMAN, ERIC P · 2001 to 2004
$4.7M
NINDS NIH HHS R01 NS040606
6 · The paper itself

Abstract

backgroundThe angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism (rs4340) (

methodsSubjects completed the Paffenbarger Physical Activity Questionnaire for weekly walking distance. Multivariate analysis of covariance (MANCOVA) tested log-transformed differences in weekly walking distance among

resultsNW adults with

conclusionBMI interacted with

Indexed as

Body mass indexexercisegenesrenin‐angiotensin aldosterone system

Identifiers

PMID28944236
PMCPMC5606874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.