ArticleRheumatology (Sunnyvale, Calif.)2017
Prevalence and Clinical Characteristics of Rheumatoid Arthritis in an Inner City Population with Sickle Cell Disease.
Article in Rheumatology (Sunnyvale, Calif.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Is the treatment of inflammatory arthritis different in sickle cell disease?Turkish journal of medical sciences · 2022Article
- Rheumatoid Arthritis Veiled by Sickle Beta-Thalassemia: A Rare Immunological Association Delaying Diagnosis.Cureus · 2021Article
- Impact of vitamin D deficiency on clinical parameters in treatment-naïve rheumatoid arthritis patients.Zeitschrift fur Rheumatologie · 2018Article
- Rheumatic Manifestations of Haemoglobinopathies.Current rheumatology reports · 2018Review
- Rheumatoid Arthritis in Sickle-Cell Population: Pathophysiologic Insights, Clinical Evaluation and Management.Rheumatology (Sunnyvale, Calif.) · 2017Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectivesRheumatoid arthritis (RA) has been rarely reported in association with sickle cell disease (SCD). Our study aimed to estimate the prevalence of RA in SCD population and to describe the clinical characteristics of RA associated with SCD.
methodsRetrospective chart review of SCD and RA patients followed at 2 large urban hospitals. Seven RA/SCD patients were identified and compared to age and sex matched cohort of SCD only and of RA only group. All patients were Black.
resultsThere were 739 SCD cases, seven (0.94%) met ACR criteria for RA (SCD-RA), 411 cases were RA only group. Mean age was significantly higher in SCD-RA compared to the entire population of SCD and RA (41.7 ± 3.9 (± SEM)
conclusionIn contrast to older reports, the prevalence of RA among SCD patients in our study (0.94%) was similar to that reported in the general population (0.5-1%) and was to be associated with difficulty in ADL and periarticular osteopenia. Since RA manifests at an older age, our reported prevalence is likely explainable by improved survival of SCD patients due to enhanced medical care and the advent of hydroxyurea as a major therapeutic breakthrough for SCD.
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