ArticleJournal of materials chemistry. B2017
One Ion to Rule Them All: Combined Antibacterial, Osteoinductive and Anticancer Properties of Selenite-Incorporated Hydroxyapatite.
Article in Journal of materials chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 80 citations in OpenAlex.
- Selenite-Doped β‑TCP Powders with Improved Biological Properties: Microwave-Assisted Synthesis and Detailed Characterization.ACS omega · 2026Article
- Development of dual acting selenium-doped hydroxyapatite nanoparticles with platinum-bisphosphonate complexes for bone cancer therapy.RSC advances · 2026Article
- Selenium anion substitution in hydroxyapatite: chemo-mechanical effects compared with root canal dentin.Odontology · 2026Article
- Incorporation of selenium nanoparticles into mineral trioxide aggregate used as a direct pulp capping material.Biomaterial investigations in dentistry · 2026Article
- Assessment of Quality in Antimicrobial Calcium Phosphate Research (AQUACAP): A Systematic Review.Materials (Basel, Switzerland) · 2025Review
- Current application and future perspectives of antimicrobial degradable bone substitutes for chronic osteomyelitis.Frontiers in bioengineering and biotechnology · 2024Review
- 3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.Bioactive materials · 2024Article
- Review
- Versatile-in-All-Trades: Multifunctional Boron-Doped Calcium-Deficient Hydroxyapatite Directs Immunomodulation and Regeneration.ACS biomaterials science & engineering · 2022Article
- Preparation of Nano-Apatite Grafted Glass-Fiber-Reinforced Composites for Orthodontic Application: Mechanical and In Vitro Biofilm Analysis.Materials (Basel, Switzerland) · 2022Article
- Porous Composite Granules with Potential Function of Bone Substitute and Simvastatin Releasing System: A Preliminary Study.Materials (Basel, Switzerland) · 2021Article
- Selenite Substituted Calcium Phosphates: Preparation, Characterization, and Cytotoxic Activity.Materials (Basel, Switzerland) · 2021Article
- Synthesis, Characterization, Antibacterial Properties, and In Vitro Studies of Selenium and Strontium Co-Substituted Hydroxyapatite.International journal of molecular sciences · 2021Article
- Synthesis and Characterization of Silver-Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles.Gels (Basel, Switzerland) · 2021Article
- Antibacterial Composite Materials Based on the Combination of Polyhydroxyalkanoates With Selenium and Strontium Co-substituted Hydroxyapatite for Bone Regeneration.Frontiers in bioengineering and biotechnology · 2021Article
- Empirical and theoretical insights into the structural effects of selenite doping in hydroxyapatite and the ensuing inhibition of osteoclasts.Materials science & engineering. C, Materials for biological applications · 2020Article
- Nanostructured selenium-doped biphasic calcium phosphate with in situ incorporation of silver for antibacterial applications.Scientific reports · 2020Article
- Comprehensive In Vitro Testing of Calcium Phosphate-Based Bioceramics with Orthopedic and Dentistry Applications.Materials (Basel, Switzerland) · 2019Review
- Emerging Anticancer Potentials of Selenium on Osteosarcoma.International journal of molecular sciences · 2019Review
- Selenium-Enriched Brushite: A Novel Biomaterial for Potential Use in Bone Tissue Engineering.International journal of molecular sciences · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Although hydroxyapatite (HAp) has been doped with dozens of different ions, the quest for an ion imparting a combination of properties conducive to bone healing is still ongoing. Because of its protean potency and the similarity in size and shape to the phosphate tetrahedron, selenite ion presents a natural ionic substitute in HAp. The incorporation of selenite into synthetic HAp using two different methods - co-precipitation and ion-exchange sorption - was studied for its effect on crystal properties and on a triad of biological responses: antibacterial, anticancer and osteoinductive. Co-precipitation yielded HAp with higher selenite contents than sorption and the stoichiometry of HAp richest in selenite was represented as Ca
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.