Evidence map›Paper›PMID 28944015›Full record

ArticleEcology and evolution2017

Signatures of selection in mammalian clock genes with coding trinucleotide repeats: Implications for studying the genomics of high-pace adaptation.

Melanie B Prentice, Jeff Bowman, Jillian L Lalor, Michelle M McKay, Lindsay A Thomson, Cristen M Watt, Andrew G McAdam, Dennis L Murray, Paul J Wilson

Erratum issuedAbstract read
In one paragraph

Article in Ecology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Melanie B PrenticeDepartment of Environmental and Life Sciences Trent University Peterborough ON Canada.ORCID 0000-0003-1445-4719
Jeff BowmanWildlife Research and Monitoring Section Ontario Ministry of Natural Resources and Forestry Peterborough ON Canada.
Jillian L LalorBiology Department Trent University Peterborough ON Canada.
Michelle M McKayDepartment of Environmental and Life Sciences Trent University Peterborough ON Canada.
Lindsay A ThomsonBiology Department Trent University Peterborough ON Canada.
Cristen M WattDepartment of Environmental and Life Sciences Trent University Peterborough ON Canada.
Andrew G McAdamDepartment of Integrative Biology University of Guelph Guelph ON Canada.
Dennis L MurrayBiology Department Trent University Peterborough ON Canada.
Paul J WilsonBiology Department Trent University Peterborough ON Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Climate change is predicted to affect the reproductive ecology of wildlife; however, we have yet to understand if and how species can adapt to the rapid pace of change. Clock genes are functional genes likely critical for adaptation to shifting seasonal conditions through shifts in timing cues. Many of these genes contain coding trinucleotide repeats, which offer the potential for higher rates of change than single nucleotide polymorphisms (SNPs) at coding sites, and, thus, may translate to faster rates of adaptation in changing environments. We characterized repeats in 22 clock genes across all annotated mammal species and evaluated the potential for selection on repeat motifs in three clock genes (

Indexed as

clock genescoding trinucleotide repeatscontemporary adaptationnatural selection

Identifiers

PMID28944015
PMCPMC5606889

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.