Evidence map›Paper›PMID 28943985›Full record

ArticlePharmacy practice

The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study.

Daniel A Erku, Asnakew A Ayele, Abebe B Mekuria, Sewunet A Belachew, Bisrat Hailemeskel, Henok G Tegegn

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacy practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 7 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 7 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  4. Effectiveness of Adherence Therapy in Adults with Type 2 Diabetes: A Systematic Review.International journal of environmental research and public health · 2021
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  7. Pharmacist services for non-hospitalised patients.The Cochrane database of systematic reviews · 2018
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  19. Impact of Diabetes Medication Therapy Adherence Clinic (DMTAC) appointment intervals on glycemic control in public health clinics across Perak, Malaysia.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2022
    Article
  20. Pharmacists' knowledge and attitudes toward medication therapy management service and the associated challenges and barriers for its implementation.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Daniel A ErkuDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar. Gondar (Ethiopia). staymotivated015@gmail.com.ORCID 0000-0002-8878-0317
Asnakew A AyeleDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar. Gondar (Ethiopia). asnake.21.uog@gmail.com.ORCID 0000-0001-7837-7228
Abebe B MekuriaDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar. Gondar (Ethiopia). abeyohannes21@gmail.com.ORCID 0000-0003-2909-2001
Sewunet A BelachewDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar. Gondar (Ethiopia). sewunet.admasu@gmail.com.ORCID 0000-0002-1050-8188
Bisrat HailemeskelAssociate Professor and Director of Drug Information Services School of Pharmacy, College of Pharmacy, Nursing, and Allied Health Sciences, Howard University. Washington, DC (United States). bhailemeskel@howard.edu.
Henok G TegegnDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar. Gondar (Ethiopia). heniget@gmail.com.ORCID 0000-0003-0644-0958
University of Gondar · ETHoward University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor adherence to antidiabetic medications leads to a higher rate of hospital admissions and adverse health outcomes in type 2 diabetes mellitus patients.

objectiveThis study aims to evaluate whether a pharmacist-led medication therapy management, compared to the usual care, could enhance medication adherence and reduce hospital admission in patients with type 2 diabetes mellitus.

methodsA prospective randomized controlled study was conducted in patients with type 2 diabetes mellitus from February 1 to July 30, 2016. Patients in the control group (n=65) received the usual care while patients in the intervention group (n=62) received a personalized pharmacotherapeutic care plan and diabetes education. The two groups were compared by repeated measure ANOVA at 3 and 6-months with medication adherence (using Morisky medication adherence scale) and number of hospital admissions as the main outcome variables.

resultsA total of 127 patients were included in the study. A marked and statistically significant increase in medication adherence from baseline to 3 and 6 months were noted in the intervention group (increased from 9.2% at baseline to 61% at 6 month) compared with the control group (increased from 13.2% at baseline (to 30.2% at 6 month; p-value<0.01). Furthermore, at the 6-month follow-up, only 23 patients in MTM group with poorly controlled blood glucose levels resulted in hospital admissions compared to 48 patients in non-MTM group, resulting in a 52.1% fewer hospital admissions (p< 0.001).

conclusionsThe findings of this study implied that pharmacist-led medication therapy management might improve medication adherence and reduce number of hospitalizations in patients with type 2 diabetes mellitus. Hence, policies and guidelines should be in place in order for clinical pharmacists to fully engage in patient care and improve the medication therapy outcomes.

Indexed as

Diabetes MellitusEthiopiaMedication AdherenceMedication Therapy ManagementPatient Education as TopicPharmacistsTreatment OutcomeType 2

Identifiers

PMID28943985
PMCPMC5597801
OpenAlexW2747336582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.