Evidence map›Paper›PMID 28943877›Full record

ArticleFrontiers in immunology2017

β-Catenin Directs Nuclear Factor-κB p65 Output

Tim Koopmans, Roos Eilers, Mark Menzen, Andrew Halayko, Reinoud Gosens

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  7. Wnt-C59 inhibits proinflammatory cytokine expression by reducing the interaction between β-catenin and NF-κB in LPS-stimulated epithelial and macrophage cells.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Tim KoopmansDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
Roos EilersDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
Mark MenzenDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
Andrew HalaykoDepartment of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB, Canada.
Reinoud GosensDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
University of Groningen · NLUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Catenin is a multifunctional protein that apart from its role in proliferative and differentiation events, also acts upon inflammatory processes, mainly

Indexed as

airway smooth musclechronic airway disordersCREB-binding proteininflammationnuclear factor-κBp300β-catenin

Identifiers

PMID28943877
PMCPMC5596077
OpenAlexW2753287992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.