Evidence map›Paper›PMID 28943861›Full record

ArticleFrontiers in endocrinology2017

A Practical and Time-Efficient High-Intensity Interval Training Program Modifies Cardio-Metabolic Risk Factors in Adults with Risk Factors for Type II Diabetes.

Bethan E Phillips, Benjamin M Kelly, Mats Lilja, Jesús Gustavo Ponce-González, Robert J Brogan, David L Morris, Thomas Gustafsson, William E Kraus, Philip J Atherton, Niels B J Vollaard and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03670186 (Effects of BDNF Val66Met Polymorphism on the Efficacy of Aerobic Exercise in Sedentary, Healthy Males), which is not on this map. Cited by 46 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 4 pooled it
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03670186 nacompletednot on this mapstarted 2018, after this paper: background citation

Effects of BDNF Val66Met Polymorphism on the Efficacy of Aerobic Exercise in Sedentary, Healthy Males

TypeinterventionalSponsorMcMaster UniversityRan2018 to 2019Enrolled18ConditionsQuality of LifeArmsHigh-Intensity Interval Training (HIIT)
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Bethan E PhillipsClinical, Metabolic and Molecular Physiology Research Group, School of Medicine, University of Nottingham, Derby, United Kingdom.
Benjamin M KellyNuffield Health, Epsom, United Kingdom.
Mats LiljaDepartment of Laboratory Medicine, Karolinska University Hospital, Stockholm, Sweden.
Jesús Gustavo Ponce-GonzálezDepartment of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
Robert J BroganScion House, Stirling University Innovation Park, Stirling, United Kingdom.
David L MorrisDivision of Genetics and Molecular Medicine, King's College London, London, United Kingdom.
Thomas GustafssonDepartment of Laboratory Medicine, Karolinska University Hospital, Stockholm, Sweden.
William E KrausDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, United States.
Philip J AthertonClinical, Metabolic and Molecular Physiology Research Group, School of Medicine, University of Nottingham, Derby, United Kingdom.
Niels B J VollaardFaculty of Health Sciences and Sport, University of Stirling, Stirling, United Kingdom.
Olav RooyackersCLINTEC, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
James A TimmonsScion House, Stirling University Innovation Park, Stirling, United Kingdom.
Karolinska University Hospital · SEKing's College London · GBUniversity of Nottingham · GBUniversity of Stirling · GBDuke University · USKarolinska Institutet · SENuffield Health · GBUniversidad de Las Palmas de Gran Canaria · ES

Funding

PERIPHERAL EFFECTS OF EXERCISE ON CARDIOVASCULAR HEALTHR01HL057354 · NHLBI · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 1998 to 2008
$5.5M
NHLBI NIH HHS R01 HL057354
6 · The paper itself

Abstract

introductionRegular physical activity (PA) can reduce the risk of developing type 2 diabetes, but adherence to time-orientated (150 min week MATERIALS AND

methodsOne hundred eighty-nine sedentary women (

resultsThe higher intensity bouts (~125% [Formula: see text]) used during a 5-by-1 min HIT protocol resulted in a robust increase in [Formula: see text] (136 participants, +10.0%,

conclusionWith a total time-commitment of <15 min per session and reliance on a practical ergometer protocol, 5-by-1 HIT offers a new solution to modulate cardio-metabolic risk factors in adults with pre-existing risk factors for type 2 diabetes while approximately meeting the MET min week

Indexed as

blood pressuredetrainingexercise[Formula: see text]healthhigh-intensity interval traininghomeostatic model assessment of insulin resistancevariability

Identifiers

PMID28943861
PMCPMC5596071
OpenAlexW2753883010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.