Evidence map›Paper›PMID 28943827›Full record

ArticleThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Levofloxacin Use in the Neonate: A Case Series.

Brandi D Newby, Kathryn E Timberlake, Lyndsay M Lepp, Tamara Mihic, Deonne A Dersch-Mills

Open access · greenAbstract readCase Reports
In one paragraph

Article in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Persistent Multidrug-ResistantCase reports in pediatrics · 2026
    Article
  3. Successful sequential therapy forFrontiers in pediatrics · 2025
    Article
  4. Stenotrophomonas maltophilia sepsis in preterm neonates.Medical journal, Armed Forces India · 2024
    Article
  5. CDC Guidelines for the Prevention and Treatment of Anthrax, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023
    Article
  6. Review
  7. Intravenous Ceftazidime-Avibactam in Extremely Premature Neonates With Carbapenem-Resistant Enterobacteriaceae: Two Case Reports.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022
    Article
  8. Safety and efficacy of colistin and fluoroquinolone in neonatal persistent late-onset sepsis.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  9. Emerging Infection withJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2018
    Article
  10. High Direct Bilirubin Associated With Levoffoxacin Use in a Neonate.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brandi D Newby
Kathryn E Timberlake
Lyndsay M Lepp
Tamara Mihic
Deonne A Dersch-Mills
St. Paul's Hospital · CAAlberta Health Services · CASt. Boniface Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report 6 cases of intravenous levofloxacin use to treat multidrug-resistant nosocomial respiratory infections in neonates with a postmenstrual age ranging from 27 to 42 weeks. Because of a lack of neonatal-specific information for levofloxacin, the usual pediatric dosage (10 mg/kg per dose every 12 hours) was used in these patients. Clinical cure occurred in 5 of the 6 patients. Only minimal short-term adverse effects were noted.

Indexed as

infantlevofloxacinmultidrug-resistant infectionneonatenewborn

Identifiers

PMID28943827
PMCPMC5562212
OpenAlexW2748757173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.