Evidence map›Paper›PMID 28943755›Full record

ArticleJournal of receptor, ligand and channel research2016

The role of the human Duffy antigen receptor for chemokines in malaria susceptibility: current opinions and future treatment prospects.

Francis B Ntumngia, Richard Thomson-Luque, Camilla V Pires, John H Adams

Open access · diamondAbstract read
In one paragraph

Article in Journal of receptor, ligand and channel research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Erythrocytes as a Source of Exerkines.International journal of molecular sciences · 2025
    Review
  3. Virtual Screening of Flavonoids againstCurrent computer-aided drug design · 2024
    Article
  4. Tropical medicine and infectious disease · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Two Genetically DistinctThe American journal of tropical medicine and hygiene · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francis B NtumngiaDepartment of Global Health, College of Public Health, University of South Florida, Tampa, FL, USA.
Richard Thomson-LuqueDepartment of Global Health, College of Public Health, University of South Florida, Tampa, FL, USA.
Camilla V PiresDepartment of Global Health, College of Public Health, University of South Florida, Tampa, FL, USA.
John H AdamsDepartment of Global Health, College of Public Health, University of South Florida, Tampa, FL, USA.
University of South Florida · US

Funding

Immunological characterization of the P. vivax DBPR01AI064478 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2006 to 2023
$9.6M
Defining epitopes of Plasmodium vivax RBP that are potential vaccine targetsR21AI107455 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI NTUMNGIA, FRANCIS BABILA · 2014 to 2015
$411k
NIAID NIH HHS R01 AI064478NIAID NIH HHS R21 AI107455
6 · The paper itself

Abstract

The Duffy antigen receptor for chemokine (DARC) is a nonspecific receptor for several proinflammatory cytokines. It is homologous to the G-protein chemokine receptor superfamily, which is suggested to function as a scavenger in many inflammatory-and proinflammatory-related diseases. G-protein chemokine receptors are also known to play a critical role in infectious diseases; they are commonly used as entry vehicles by infectious agents. A typical example is the chemokine receptor CCR5 or CXCR4 used by HIV for infecting target cells. In malaria, DARC is considered an essential receptor that mediates the entry of the human and zoonotic malaria parasites

Indexed as

DARCknowlesimalariaPlasmodiumtreatmentvivax

Identifiers

PMID28943755
PMCPMC5608092
OpenAlexW2524702869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.