Evidence map›Paper›PMID 28943566›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Deep Ulcers in the Ileum Associated with Mycophenolate Mofetil.

Akira Sonoda, Kurato Wada, Kazuhiro Mizukami, Kensuke Fukuda, Mitsutaka Shuto, Kazuhisa Okamoto, Ryo Ogawa, Tadayoshi Okimoto, Kazunari Murakami

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Akira SonodaDepartment of Gastroenterology, Oita University, Japan.
Kurato WadaDepartment of Gastroenterology, Oita University, Japan.
Kazuhiro MizukamiDepartment of Gastroenterology, Oita University, Japan.
Kensuke FukudaDepartment of Gastroenterology, Oita University, Japan.
Mitsutaka ShutoDepartment of Gastroenterology, Oita University, Japan.
Kazuhisa OkamotoDepartment of Gastroenterology, Oita University, Japan.
Ryo OgawaDepartment of Gastroenterology, Oita University, Japan.
Tadayoshi OkimotoDepartment of Gastroenterology, Oita University, Japan.
Kazunari MurakamiDepartment of Gastroenterology, Oita University, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 54-year-old man was treated with mycophenolate mofetil (MMF) after undergoing living donor renal transplantation. Two years later, he experienced repeated episodes of diarrhea, and his C-reactive protein (CRP) level was found to be 12.63 mg/dL. Ileocolonoscopy showed multiple deep, punched-out ulcers that were similar to Behçet's disease (BD) and cytomegalovirus (CMV) in the ileum. CMV infection was suspected. However, anti-cytomegalovirus agents were ineffective. The patient was subsequently diagnosed with gastrointestinal toxicity of MMF and MMF was switched to mizoribine. His symptoms improved immediately, and his CRP level normalized. Six months later, the patient's mucosa was healed.

Indexed as

C-Reactive ProteinGraft RejectionHumansIleal DiseasesImmunosuppressive AgentsKidney TransplantationMaleMiddle AgedMycophenolic AcidUlcerC-Reactive ProteinImmunosuppressive AgentsMycophenolic Acidgastrointestinal toxicityileal ulcermycophenolate mofetilrenal transplantation

Identifiers

PMID28943566
PMCPMC5709631
OpenAlexW2757362443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.