Evidence map›Paper›PMID 28943467›Full record

ArticleThe Journal of allergy and clinical immunology2018

Concomitant suppression of T

Hyeongjin Na, Hoyong Lim, Garam Choi, Byung-Keun Kim, Sae-Hoon Kim, Yoon-Seok Chang, Roza Nurieva, Chen Dong, Seon Hee Chang, Yeonseok Chung

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Regulation of mCell biology and toxicology · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. T helper 2 cells in asthma.The Journal of experimental medicine · 2023
    Review
  11. Review
  12. Article
  13. AMPK suppresses Th2 cell responses by repressing mTORC2.Experimental & molecular medicine · 2022
    Article
  14. Article
  15. TThe Journal of allergy and clinical immunology · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 5 countries.

Hyeongjin NaLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul, Korea.
Hoyong LimLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea.
Garam ChoiLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul, Korea.
Byung-Keun KimDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Sae-Hoon KimDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Yoon-Seok ChangDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Roza NurievaDepartment of Immunology, MD Anderson Cancer Center, Houston, Tex.
Chen DongInstitute for Immunology and School of Medicine, Tsinghua University, Beijing, China.
Seon Hee ChangDepartment of Immunology, MD Anderson Cancer Center, Houston, Tex. Electronic address: shchang@mdanderson.org.
Yeonseok ChungLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul, Korea. Electronic address: yeonseok@snu.ac.kr.
Seoul National University · KRSeoul National University Bundang Hospital · KRThe University of Texas MD Anderson Cancer Center · USTsinghua University · CN

Funding

STAT1: New regulator of inflammatory Th17 and Th2 cellsR21AI120012 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI NURIEVA, ROZA INSAFETDINOVNA · 2016 to 2017
$440k
Role of Cul4A in Th2 tolerance and airway inflammationR56AI125269 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI NURIEVA, ROZA INSAFETDINOVNA · 2017 to 2017
$300k
Role of Grail in maintaining humoral immune toleranceR03AI120027 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI NURIEVA, ROZA INSAFETDINOVNA · 2015 to 2016
$160k
Grail-targeting breaks the immune tolerance to melanomaR03CA219760 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI NURIEVA, ROZA INSAFETDINOVNA · 2017 to 2018
$160k
NCI NIH HHS R03 CA219760NIAID NIH HHS R03 AI120027NIAID NIH HHS R21 AI120012NIAID NIH HHS R56 AI125269
6 · The paper itself

Abstract

backgroundAllergic asthma is a heterogeneous chronic inflammatory disease of the airways with a massive infiltration of eosinophils or neutrophils mediated by allergen-specific T

objectiveWe sought to investigate the role of the T

methodsAllergic asthma was induced by intranasal challenge with proteinase allergens in C57BL/6, Il17a

resultsMice deficient in IL-17A and IL-17F, as well as RORγt, exhibited a significant reduction not only in T

conclusionRORγt in T cells is required for optimal T

Indexed as

AnimalsAsthmaCell DifferentiationHumansMiceMice, Inbred C57BLMice, KnockoutNuclear Receptor Subfamily 1, Group F, Member 3Th17 CellsTh2 CellsNuclear Receptor Subfamily 1, Group F, Member 3Allergic asthmaB-cell lymphoma 6retinoic acid receptor–related orphan receptor γtT(H)17 cellT(H)2 cell

Identifiers

PMID28943467
PMCPMC5862762
OpenAlexW2758759492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.