Evidence map›Paper›PMID 28943254›Full record

ArticleStem cell reports2017

SOX7 Is Required for Muscle Satellite Cell Development and Maintenance.

Rashida F Rajgara, Neena Lala-Tabbert, François Marchildon, Émilie Lamarche, Jennifer K MacDonald, Daryl A Scott, Alexandre Blais, Ilona S Skerjanc, Nadine Wiper-Bergeron

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. International journal of dentistry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Rashida F RajgaraDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada; Graduate Program in Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Neena Lala-TabbertDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
François MarchildonGraduate Program in Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Émilie LamarcheGraduate Program in Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Jennifer K MacDonaldDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Daryl A ScottDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Alexandre BlaisDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Ilona S SkerjancDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Nadine Wiper-BergeronDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. Electronic address: nadine.wiperbergeron@uottawa.ca.
University of Ottawa · CABaylor College of Medicine · US

Funding

CIHR 115029CIHR MOP-84458
6 · The paper itself

Abstract

Satellite cells are skeletal-muscle-specific stem cells that are activated by injury to proliferate, differentiate, and fuse to enable repair. SOX7, a member of the SRY-related HMG-box family of transcription factors is expressed in quiescent satellite cells. To elucidate SOX7 function in skeletal muscle, we knocked down Sox7 expression in embryonic stem cells and primary myoblasts and generated a conditional knockout mouse in which Sox7 is excised in PAX3

Indexed as

AnimalsCell DifferentiationCell LineCell Self RenewalCell SurvivalEmbryonic Stem CellsGene ExpressionGene Knockout TechniquesMiceMice, KnockoutMuscle DevelopmentMuscle Fibers, SkeletalMyoblastsRegenerationSatellite Cells, Skeletal MuscleSOXF Transcription FactorsSox7 protein, mouseSOXF Transcription Factorsconditional knockoutembryonic stem cellmuscle regenerationmuscle satellite cellsmyogenesisPAX3PAX7SOX7

Identifiers

PMID28943254
PMCPMC5639291
OpenAlexW2760620111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.