ArticleCurrent biology : CB2017
Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.
- Overview of molecular mechanisms of plant leaf development: a systematic review.Frontiers in plant science · 2023Pooled it
- Growth directions and stiffness across cell layers determine whether tissues stay smooth or buckle.Current biology : CB · 2026Article
- The CmYAB1-CmCUC2 transcriptional module shapes the iconic ray florets in Chrysanthemum morifolium.The New phytologist · 2026Article
- Transcriptomic Analysis of Phylloclade inPlants (Basel, Switzerland) · 2026Article
- Quantitative trait loci mapping of heterosis for leaf morphological traits and candidate gene identification in maize.BMC plant biology · 2026Article
- Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.Plants (Basel, Switzerland) · 2025Review
- Article
- CRISPR/Cas9-Mediated Targeted Mutagenesis ofInternational journal of molecular sciences · 2025Article
- The Effect of Far-Red Light on the Growth of Tobacco Leaves.Plants (Basel, Switzerland) · 2025Article
- JAG modulates sepal flatness by regulating cell growth direction, interacts with AS2, and is antagonized by TCP24.Cell reports · 2025Article
- Functional Characterization ofPlants (Basel, Switzerland) · 2025Article
- Stem Cell Factors BAM1 and WOX1 Suppressing Longitudinal Cell Division of Margin Cells Evoked by Low-Concentration Auxin in Young Cotyledon of Arabidopsis.International journal of molecular sciences · 2025Article
- Genome-Wide Identification of theInternational journal of molecular sciences · 2025Article
- Conserved roles of ETT and ARF4 in gynoecium development in Brassicaceae with distinct fruit shapes.Development (Cambridge, England) · 2025Article
- Identification of candidate genes for leaf size by QTL mapping and transcriptome sequencing in Brassica napus L.BMC genomics · 2025Article
- Functional Divergence of the Closely Related Genes PhARF5 and PhARF19a inInternational journal of molecular sciences · 2024Article
- Functional Analysis ofInternational journal of molecular sciences · 2024Article
- A 3-component module maintains sepal flatness in Arabidopsis.Current biology : CB · 2024Article
- Transcriptomic profiling reveals histone acetylation-regulated genes involved in somatic embryogenesis in Arabidopsis thaliana.BMC genomics · 2024Article
- Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
The flattening of leaves to form broad blades is an important adaptation that maximizes photosynthesis. However, the molecular mechanism underlying this process remains unclear. The WUSCHEL-RELATED HOMEOBOX (WOX) genes WOX1 and PRS are expressed in the leaf marginal domain to enable leaf flattening, but the nature of WOX expression establishment remains elusive. Here, we report that adaxial-expressed MONOPTEROS (MP) and abaxial-enriched auxin together act as positional cues for patterning the WOX domain. MP directly binds to the WOX1 and PRS promoters and activates their expression. Furthermore, redundant abaxial-enriched ARF repressors suppress WOX1 and PRS expression, also through direct binding. In particular, we show that ARF2 is redundantly required with ARF3 and ARF4 to maintain the abaxial identity. Taken together, these findings explain how adaxial-abaxial polarity patterns the mediolateral axis and subsequent lateral expansion of leaves.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.