Evidence map›Paper›PMID 28941998›Full record

Trial reportThe Journal of steroid biochemistry and molecular biology2018

Vitamin D

Amy E Riek, Jisu Oh, Isra Darwech, Veronica Worthy, Xiaobo Lin, Richard E Ostlund, Rong M Zhang, Carlos Bernal-Mizrachi

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of steroid biochemistry and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Amy E RiekDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: aeriek@wustl.edu.
Jisu OhDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: joh@wustl.edu.
Isra DarwechDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: idarwech@wustl.edu.
Veronica WorthyDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: vworthy@wustl.edu.
Xiaobo LinDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: xlin22@wustl.edu.
Richard E OstlundDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: rostlund@wustl.edu.
Rong M ZhangDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA. Electronic address: cbernal@wustl.edu.
Carlos Bernal-MizrachiDivision of Endocrinology, Metabolism, and Lipid Research, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA; Department of Cell Biology and Physiology, Washington University, 660 South Euclid Ave., Campus Box 8127, St. Louis, MO 63110, USA; Division of Endocrinology at Saint Louis VA Medical Center, 915 N Grant Blvd, Saint Louis, MO, 63106, USA. Electronic address: cbernal@wustl.edu.
Washington University in St. Louis · USSt. Louis VA Medical Center · US

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1M
DIABETES &RELATED METABOLIC DISEASEST32DK007120 · NIDDK · WASHINGTON UNIVERSITY · PI MARCO COLONNA, Maria Sara Remedi · 1986 to 2026
$15.7M
VITAMIN D DEFICIENCY, INSULIN RESISTANCE AND CARDIOVASCULAR DISEASER01HL094818 · NHLBI · WASHINGTON UNIVERSITY · PI Carlos Bernal-Mizrachi · 2010 to 2026
$6.3M
NHLBI NIH HHS R01 HL094818NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341NIDDK NIH HHS T32 DK007120
6 · The paper itself

Abstract

Cross-sectional studies indicate consistent associations between low 25(OH)D concentration and increased risk of cardiovascular disease (CVD), but results of randomized control trials (RCTs) are mixed. However, the majority of the RCTs do not focus on type 2 diabetics, potentially obscuring the effects of vitamin D in this population. In vitro 1,25(OH)

Indexed as

Dietary SupplementsCD36 AntigensCholecalciferolCholesterolDiabetes Mellitus, Type 2Double-Blind MethodEndoplasmic Reticulum StressFemaleHumansMaleMiddle AgedMonocytesVitaminsCD36 AntigensCD36 protein, humanCholecalciferolCholesterolVitaminsAtherosclerosisCD36Cholesterol metabolismMonocytesVitamin D

Identifiers

PMID28941998
PMCPMC5826751
OpenAlexW2760512984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.