Evidence map›Paper›PMID 28941622›Full record

ArticleVaccine2018

Epidemiology of childhood intussusception in Bangladesh: Findings from an active national hospital based surveillance system, 2012-2016.

Syed M Satter, Negar Aliabadi, Catherine Yen, Paul A Gastañaduy, Makhdum Ahmed, Abdullah Mamun, Khaleda Islam, Meerjady S Flora, Mahmudur Rahman, K Zaman and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Syed M Sattericddr,b, Bangladesh. Electronic address: dr.satter@icddrb.org.
Negar AliabadiCenters for Disease Control and Prevention (CDC), Atlanta, USA.
Catherine YenCenters for Disease Control and Prevention (CDC), Atlanta, USA.
Paul A GastañaduyCenters for Disease Control and Prevention (CDC), Atlanta, USA.
Makhdum AhmedThe University of Texas MD Anderson Cancer Center, Houston, USA.
Abdullah MamunUBC and Vancouver General Hospital, Vancouver, Canada.
Khaleda IslamInstitute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh.
Meerjady S FloraInstitute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh.
Mahmudur RahmanInstitute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh.
K Zamanicddr,b, Bangladesh.
Mustafizur Rahmanicddr,b, Bangladesh.
James D HeffelfingerCenters for Disease Control and Prevention (CDC), Atlanta, USA.
Stephen P LubyCenter for Innovation in Global Health, Stanford University, USA.
Emily S Gurleyicddr,b, Bangladesh.
Umesh D ParasharCenters for Disease Control and Prevention (CDC), Atlanta, USA.
Centers for Disease Control and Prevention · USInstitute of Epidemiology, Disease Control and Research · BDInternational Centre for Diarrhoeal Disease Research · BDStanford University · USThe University of Texas MD Anderson Cancer Center · USVancouver General Hospital · CA

Funding

CGH CDC HHS U51 GH001209Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionRotavirus vaccines have significantly decreased the burden of diarrheal diseases in countries that have introduced them into their immunization programs. In some studies, there has been a small association between rotavirus vaccines and intussusception in post-marketing surveillance, highlighting the importance of tracking incidence before and after vaccine introduction. The objective of this study was to describe the epidemiology of intussusception among Bangladeshi children pre-vaccine introduction.

methodsWe conducted active, hospital-based surveillance for intussusception at 7 tertiary care hospitals with pediatric surgical facilities during July 2012 to September 2016. Hospitalized children under 2years of age were identified according to Brighton Collaboration level 1 criteria for intussusception. The frequency and proportion of intussusception among overall surgical admissions, as well as the demographic and clinical information of the cases is described.

resultsOverall 153 cases of intussusception among children <2years-old were identified at participating sites over the enrolment period, confirmed by Level 1 Brighton criteria. These cases represented 2% of all surgical admissions under 2years of age. One hundred twelve cases (73%) were male; the median age was 7months; and the median duration of hospitalization was 7days. One hundred forty-six (95%) children with intussusception required surgery, and 11 (7%) died.

conclusionsConfirmed cases of intussusception represented nearly 2% of pediatric surgical admissions at tertiary referral centers in Bangladesh during the study period and 7% of children with intussusception died. Given the high burden of rotavirus disease in Bangladesh, vaccine introduction is warranted, however, further studies after introduction of rotavirus vaccine are necessary to determine any association between vaccine and intussusception in this setting.

Indexed as

Epidemiological MonitoringBangladeshCost of IllnessDiarrheaFemaleHospitalizationHumansIncidenceInfantInfant, NewbornIntussusceptionMaleRotavirus InfectionsRotavirus VaccinesTertiary Care CentersVaccinationRotavirus VaccinesBangladeshHospital based surveillanceIntussusceptionRotavirusRotavirus vaccination

Identifiers

PMID28941622
PMCPMC5864564
OpenAlexW2755475964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.