Evidence map›Paper›PMID 28941619›Full record

ArticleVaccine2017

An ensemble approach to predicting the impact of vaccination on rotavirus disease in Niger.

Jaewoo Park, Joshua Goldstein, Murali Haran, Matthew Ferrari

Abstract read
In one paragraph

Article in Vaccine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Estimating the global impact of rotavirus vaccines on child mortality.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jaewoo ParkDepartment of Statistics, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address: jzp191@psu.edu.
Joshua GoldsteinSocial and Data Analytics Laboratory, 900 N Glebe Rd, Virginia Tech, Arlington, VA 22203, USA. Electronic address: joshg22@vbi.vt.edu.
Murali HaranDepartment of Statistics, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address: muh10@psu.edu.
Matthew FerrariDepartment of Biology, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address: mjf283@psu.edu.

Funding

Linking models and policy: Using active adaptive management for optimal control of disease outbreaksR01GM105247 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI FERRARI, MATTHEW · 2012 to 2016
$1.3M
NIGMS NIH HHS R01 GM105247
6 · The paper itself

Abstract

Recently developed vaccines provide a new way of controlling rotavirus in sub-Saharan Africa. Models for the transmission dynamics of rotavirus are critical both for estimating current burden from imperfect surveillance and for assessing potential effects of vaccine intervention strategies. We examine rotavirus infection in the Maradi area in southern Niger using hospital surveillance data provided by Epicentre collected over two years. Additionally, a cluster survey of households in the region allows us to estimate the proportion of children with diarrhea who consulted at a health structure. Model fit and future projections are necessarily particular to a given model; thus, where there are competing models for the underlying epidemiology an ensemble approach can account for that uncertainty. We compare our results across several variants of Susceptible-Infectious-Recovered (SIR) compartmental models to quantify the impact of modeling assumptions on our estimates. Model-specific parameters are estimated by Bayesian inference using Markov chain Monte Carlo. We then use Bayesian model averaging to generate ensemble estimates of the current dynamics, including estimates of R

Indexed as

Bayes TheoremChild, PreschoolDiarrheaHumansImmunization ScheduleInfantInfant, NewbornMarkov ChainsMonte Carlo MethodNigerRotavirusRotavirus InfectionsRotavirus VaccinesVaccinationRotavirus VaccinesBayesian model averagingNigerRotavirusSusceptible-Infectious-Recovered modelsVaccine

Identifiers

PMID28941619
PMCPMC7185385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.