ArticleThe Lancet. Infectious diseases2017
The global burden of scabies: a cross-sectional analysis from the Global Burden of Disease Study 2015.
Article in The Lancet. Infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06918665 (HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence), which is not on this map. Cited by 139 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence: Infant Versus Standard Formulation
Who cites it
139 citing papers in PubMed, 5 syntheses or guidelines pooled it, 329 citations in OpenAlex.
- Burden of scabies in displacement settings: A systematic review and meta-analysis among forcibly displaced populations.PLoS neglected tropical diseases · 2025Pooled it
- Prevalence and determinants of scabies: A global systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2024Pooled it
- Pooled it
- Organizational Factors Determining Access to Reperfusion Therapies in Ischemic Stroke-Systematic Literature Review.International journal of environmental research and public health · 2022Pooled it
- Ivermectin and permethrin for treating scabies.The Cochrane database of systematic reviews · 2018Pooled it
- Efficacy of mass drug administration with ivermectin for control of scabies and impetigo, with coadministration of azithromycin: a single-arm community intervention trial.The Lancet. Infectious diseases · 2019Trial
- Temporal trends in scabies-related emergency department visits: a retrospective trend analysis of 10,994 visits.Annals of medicine · 2026Article
- Anatomical Distribution of Scabies Lesions and Factors Associated With Typical Anatomical-Site Involvement Among Patients Attending a Dermatology Center in Mogadishu, Somalia: A Facility-Based Cross-Sectional Study.Health science reports · 2026Article
- A Case-Control Study of Risk Factors for Scabies Among Patients Attending Dermatology Clinics in Afghanistan.Health science reports · 2026Article
- Time trends in the burden of scabies from 1990 to 2021, and projections to 2050: Insights based on the Global Burden of Disease Study 2021.PLoS neglected tropical diseases · 2026Article
- Massive scabies outbreak in Rohingya refugee camps, Cox's Bazar: Epidemiology and impact of a mass drug administration (MDA) campaign - A retrospective study.PLoS neglected tropical diseases · 2026Observational
- Factors associated with scabies severity and reinfection: A cross-sectional study during recent surges in the Chattogram Division, Bangladesh.IJID regions · 2026Article
- Observational
- Article
- Human scabies and pediculosis in Ecuador: spatial distribution and environmental determinants.Parasitology · 2026Article
- Prolonged Post-Scabietic Pruritus: Clinical Characteristics and Unmet Management Needs in a Real-World Cohort.Journal of clinical medicine · 2026Article
- Structure of a pH-sensitive pentameric ligand-gated ion channel from the Sarcoptes scabies mite.Nature communications · 2026Article
- Burden of liver cancer from 1990 to 2021 and modelled projection to 2040: insights from the global burden of disease study 2021.Frontiers in oncology · 2026Article
- Phytomedicines and conventional drugs in scabies management.GMS hygiene and infection control · 2026Review
- Why does scabies persist despite effective treatment? Coordination failure, Nash equilibrium, and replicator dynamics.Frontiers in public health · 2026Article
79 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNumerous population-based studies have documented high prevalence of scabies in overcrowded settings, particularly among children and in tropical regions. We provide an estimate of the global burden of scabies using data from the Global Burden of Disease (GBD) Study 2015.
methodsWe identified scabies epidemiological data sources from an extensive literature search and hospital insurance data and analysed data sources with a Bayesian meta-regression modelling tool, DisMod-MR 2·1, to yield prevalence estimates. We combined prevalence estimates with a disability weight, measuring disfigurement, itch, and pain caused by scabies, to produce years lived with disability (YLDs). With an assumed zero mortality from scabies, YLDs were equivalent to disability-adjusted life-years (DALYs). We estimated DALYs for 195 countries divided into 21 world regions, in both sexes and 20 age groups, between 1990 and 2015.
findingsScabies was responsible for 0·21% of DALYs from all conditions studied by GBD 2015 worldwide. The world regions of east Asia (age-standardised DALYs 136·32), southeast Asia (134·57), Oceania (120·34), tropical Latin America (99·94), and south Asia (69·41) had the greatest burden of DALYs from scabies. Mean percent change of DALY rate from 1990 to 2015 was less than 8% in all world regions, except North America, which had a 23·9% increase. The five individual countries with greatest scabies burden were Indonesia (age-standardised DALYs 153·86), China (138·25), Timor-Leste (136·67), Vanuatu (131·59), and Fiji (130·91). The largest standard deviations of age-standardised DALYs between the 20 age groups were observed in southeast Asia (60·1), Oceania (58·3), and east Asia (56·5), with the greatest DALY burdens in children, adolescents, and the elderly.
interpretationThe burden of scabies is greater in tropical regions, especially in children, adolescents, and elderly people. As a worldwide epidemiological assessment, GBD 2015 provides broad and frequently updated measures of scabies burden in terms of skin effects. These global data might help guide research protocols and prioritisation efforts and focus scabies treatment and control measures.
fundingBill & Melinda Gates Foundation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.