Evidence map›Paper›PMID 28941524›Full record

ReviewSeminars in pediatric neurology2017

Juvenile Macular Degenerations.

Pablo Altschwager, Lucia Ambrosio, Emily A Swanson, Anne Moskowitz, Anne B Fulton

Abstract readReview
In one paragraph

Review in Seminars in pediatric neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Preferred Retinal Locus in Juvenile Macular Dystrophy.Turkish journal of ophthalmology · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Eye Movements in Macular Degeneration.Annual review of vision science · 2021
    Review
  11. Measurement of macular thickness with optical coherence tomography: impact of using a paediatric reference database and analysis of interocular symmetry.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Pablo AltschwagerDepartamento de Oftalmología, Escuela de Medicina, Pontificia, Universidad Católica de Chile, Santiago, Chile. Electronic address: paltschwager@med.puc.cl.
Lucia AmbrosioDepartment of Ophthalmology, Children׳s Hospital, Boston, MA; Department of Ophthalmology, Harvard Medical School, Boston, MA.
Emily A SwansonDepartment of Ophthalmology, Children׳s Hospital, Boston, MA.
Anne MoskowitzDepartment of Ophthalmology, Children׳s Hospital, Boston, MA; Department of Ophthalmology, Harvard Medical School, Boston, MA.
Anne B FultonDepartment of Ophthalmology, Children׳s Hospital, Boston, MA; Department of Ophthalmology, Harvard Medical School, Boston, MA.
Harvard University · USBoston Children's Hospital · USPontificia Universidad Católica de Chile · CL

Funding

Compact Line Scanning Adaptive Optics Retinal ImagerR44EY018509 · NEI · PHYSICAL SCIENCES, INC · PI MUJAT, MIRCEA · 2010 to 2015
$2.1M
Compact Line-scanning Adaptive Optics Retinal ImagerR43EY018509 · NEI · PHYSICAL SCIENCES, INC · PI HAMMER, DANIEL XAVIER · 2007 to 2007
$201k
NEI NIH HHS R43 EY018509NEI NIH HHS R44 EY018509
6 · The paper itself

Abstract

In this article, we review the following 3 common juvenile macular degenerations: Stargardt disease, X-linked retinoschisis, and Best vitelliform macular dystrophy. These are inherited disorders that typically present during childhood, when vision is still developing. They are sufficiently common that they should be included in the differential diagnosis of visual loss in pediatric patients. Diagnosis is secured by a combination of clinical findings, optical coherence tomography imaging, and genetic testing. Early diagnosis promotes optimal management. Although there is currently no definitive cure for these conditions, therapeutic modalities under investigation include pharmacologic treatment, gene therapy, and stem cell transplantation.

Indexed as

ChildHumansMacula LuteaMacular DegenerationRetinoschisisStargardt DiseaseVitelliform Macular Dystrophy

Identifiers

PMID28941524
PMCPMC5709045
OpenAlexW2619827141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.