Evidence map›Paper›PMID 28941467›Full record

ArticleJournal of medical case reports2017

An atypical presentation of cardiac tamponade and periorbital swelling in a patient with eosinophilic granulomatosis with polyangiitis: a case report.

Alexandra C Keefe, Joseph C Hymas, Lyska L Emerson, John J Ryan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alexandra C KeefeDepartment of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
Joseph C HymasGeneral Cardiology, St. Luke's Hospital, Twin Falls, ID, USA.
Lyska L EmersonDepartment of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT, USA.
John J RyanDepartment of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. john.ryan@hsc.utah.edu.
University of Utah · USARUP Laboratories (United States) · USSt. Luke's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEosinophilic granulomatosis with polyangiitis is a rare, necrotizing systemic vasculitis associated with asthma and hypereosinophilia. Its cause and pathophysiology are still being elucidated. CASE PRESENTATION: We report a case of eosinophilic granulomatosis with polyangiitis in a 50-year-old Caucasian woman who presented with chest pain, dyspnea at rest, fever, and periorbital swelling. She was found to have significant hypereosinophilia and cardiac tamponade physiology. A biopsy confirmed extensive infiltration of both lungs and pericardium by eosinophils. She did not have any anti-neutrophil cytoplasmic antibodies.

conclusionsEosinophilic granulomatosis with polyangiitis diagnosis does not require the presence of anti-neutrophil cytoplasmic antibodies. Anti-neutrophil cytoplasmic antibody-positive and anti-neutrophil cytoplasmic antibody-negative eosinophilic granulomatosis with polyangiitis may present with different clinical phenotypes, perhaps suggesting two distinct disease etiologies and distinct pathophysiology.

Indexed as

OrbitAntibodies, Antineutrophil CytoplasmicBiopsyCardiac TamponadeChurg-Strauss SyndromeDyspneaEdemaEosinophiliaFemaleFeverHumansLungMiddle AgedPericardiumAntibodies, Antineutrophil CytoplasmicCardiac tamponadeChurg-Strauss syndromeEffusionPeriorbital swellingVasculitis

Identifiers

PMID28941467
PMCPMC5610727
OpenAlexW2754270932

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.