Trial reportJournal of clinical hypertension (Greenwich, Conn.)2017
Mobile phone text messaging improves antihypertensive drug adherence in the community.
Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 11 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 11 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Theory-Based Interventions to Improve Medication Adherence Among Patients With Hypertension in Primary Healthcare and the Community: A Systematic Review.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025Pooled it
- A Systematic Review of Compensation and Technology-Mediated Strategies to Maintain Older Adults' Medication Adherence.International journal of environmental research and public health · 2023Pooled it
- Pooled it
- Effectiveness of Text Messaging Interventions on Blood Pressure Control Among Patients With Hypertension: Systematic Review of Randomized Controlled Trials.JMIR mHealth and uHealth · 2021Pooled it
- Mobile Phone Technologies in the Management of Ischemic Heart Disease, Heart Failure, and Hypertension: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2020Pooled it
- Interventions for improving medication-taking ability and adherence in older adults prescribed multiple medications.The Cochrane database of systematic reviews · 2020Pooled it
- How Behavior Change Strategies are Used to Design Digital Interventions to Improve Medication Adherence and Blood Pressure Among Patients With Hypertension: Systematic Review.Journal of medical Internet research · 2020Pooled it
- The Effectiveness of Self-Management of Hypertension in Adults Using Mobile Health: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2020Pooled it
- Influence of reminder therapy for controlling bacterial plaque in patients undergoing orthodontic treatment: A systematic review and meta-analysis.The Angle orthodontist · 2018Pooled it
- Mobile phone text messaging to improve medication adherence in secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017Pooled it
- Community-Based Interventions for Hypertension Control in Latin America and the Caribbean: A Systematic Review of Randomized Controlled Trials.Journal of primary care & community healthPooled it
- Behavioral Economics and Medication Adherence for Hypertension: A Randomized Clinical Trial.Journal of the American College of Cardiology · 2026Trial
- Internet-based digital intervention to support the self-management of hypertension compared to usual care: results of the HALCYON randomized controlled trial.BMC cardiovascular disorders · 2025Trial
- Efficacy of short message service (SMS) intervention on medication adherence and knowledge of stroke prevention among clinic attendees at risk of stroke: a randomized controlled trial.BMC public health · 2025Trial
- The role of training and medication reminder wristwatch in adherence to treatment in geriatric patients diagnosed with hypertension: A randomized controlled trial.Geriatrics & gerontology international · 2024Trial
- Effectiveness of a Multifaceted Mobile Health Intervention (Multi-Aid-Package) in Medication Adherence and Treatment Outcomes Among Patients With Hypertension in a Low- to Middle-Income Country: Randomized Controlled Trial.JMIR mHealth and uHealth · 2024Trial
- Use of text messages to promote medication adherence and reduce blood pressure in patients with hypertension: the ESSENCE study.Cadernos de saude publica · 2024Trial
- Description of patient questions received by clinical pharmacists in the Nudge Study.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2023Trial
- Trial
- Effect ofPrimary health care research & development · 2022Trial
Corrections and comments
- Commented on by
Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antihypertensive drug adherence (ADA) is a mainstay in blood pressure control. Education through mobile phone short message system (SMS) text messaging could improve ADA. The authors conducted a randomized study involving 314 patients with hypertension with <6 months of antihypertensive treatment from the Preventive Health Program of 12 different primary care centers in Santiago, Chile. Patients were randomly assigned to receive or not receive SMS related to ADA and healthy lifestyle. Adherence was assessed by the self-reported four-item scale Morisky-Green-Levine questionnaire at baseline and after 6 months of follow-up, with four of four positive questions classified as good adherence. Group comparison for adherence was performed by means of a logistic regression model, adjusting by baseline adherence, age older than 60 years, and sex. A total of 163 patients were randomized to receive and 151 to not receive SMS. After 6 months of follow-up, ADA in the non-SMS group decreased from 59.3% to 51.4% (P=.1). By contrast, adherence increased from 49% to 62.3% (P=.01) in the SMS group. Text messaging intervention improved ADA (risk ratio, 1.3; 95% confidence interval, 1.0-1.6 [P<.05]). At 6-month follow-up, text messaging resulted in an increase in reporting ADA in this hypertensive Latino population. This approach could become an effective tool to overcome poor medication adherence in the community.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.